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Results: 556
Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients.
Xiaoke Yin 殷晓科, Shaynah Wanga, Adam L Fellows, Javier Barallobre-Barreiro, Ruifang Lu, Hongorzul Davaapil, Romy Franken, Marika Fava, Ferheen Baig, Philipp Skroblin, Qiuru Xing, David R Koolbergen, Maarten Groenink, Aeilko H Zwinderman, Ron Balm, Carlie JM de Vries, Barbara JM Mulder, Rosa Viner, Marjan Jahangiri, Dieter P Reinhardt, Sanjay Sinha, Vivian de Waard, Manuel Mayr
Jul 25, 2019
OBJECTIVE: Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally by glycosylation. This study aimed to characterize the glycoproteome...
Pharmacogenomics and the Yin/Yang actions of ginseng
Patrick Ying Kit Yue, Nai Ki Mak, Yuen Kit Cheng, Kar Wah Leung, Tzi Bun Ng, David Tai Ping Fan, Hin Wing Yeung, Ricky Ngok Shun Wong
Jun 16, 2011
In Chinese medicine, ginseng (Panax ginseng C.A. Meyer) has long been used as a general tonic or an adaptogen to promote longevity and enhance bodily functions. It has also been claimed to be effective in combating stress...
Behavior Recognition of College Students Based on Improved Deep Learning Algorithm
Xiaoke Ning
Feb 23, 2023
With the vigorous development of intelligent campus construction, great changes have taken place in the development of information technology in colleges and universities from the previous digital to intelligent development. In...
Published by: IGI Global Scientific Publishing
Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation.
Adam A Nabeebaccus, Anna Zoccarato, Anne D Hafstad, Celio Xc Santos, Ellen Aasum, Alison C Brewer, Min Zhang, Matteo Beretta, Xiaoke Yin, James A West, Katrin Schröder, Julian L Griffin, Thomas R Eykyn, E Dale Abel, Manuel Mayr, Ajay M Shah
Jan 15, 2018
Cardiac hypertrophic remodeling during chronic hemodynamic stress is associated with a switch in preferred energy substrate from fatty acids to glucose, usually considered to be energetically favorable. The mechanistic...
Cardiology cardiovascular disease Intermediary metabolism metabolism Signal Transduction Acetylglucosamine Adaptation Physiological Animals Cardiomegaly Energy Metabolism Fatty Acids Glucose Glycolysis Hexosamines Mice Knockout Mice Transgenic Myocardium Myocytes Cardiac NADPH Oxidase 4 Oxidation-Reduction Proteome Stress Physiological
Serial Interval of COVID-19 among Publicly Reported Confirmed Cases.
We estimate the distribution of serial intervals for 468 confirmed cases of coronavirus disease reported in China as of February 8, 2020. The mean interval was 3.96 days (95% CI 3.53-4.39 days), SD 4.75 days (95% CI 4.46-5.07...
2019 novel coronavirus disease covid-19 China SARS-CoV-2 Wuhan coronavirus EPIDEMIOLOGY respiratory infections serial interval severe acute respiratory syndrome coronavirus 2 viruses Zoonoses Basic Reproduction Number Betacoronavirus covid-19 China Coronavirus Infections Humans Pandemics Pneumonia Viral SARS-CoV-2 Time Factors
Balancing the yin and yang
This paper offers a novel theoretical account of why and when top management team (TMT) gender diversity lends strategic advantage. Building on social role theory, we develop a moderated-mediation model showing: a) TMT...
Risk for Transportation of Coronavirus Disease from Wuhan to Other Cities in China.
Zhanwei Du, Lin Wang, Simon Cauchemez, Xiaoke Xu, Xianwen Wang, Benjamin J Cowling, Lauren Ancel Meyers
May 05, 2020
On January 23, 2020, China quarantined Wuhan to contain coronavirus disease (COVID-19). We estimated the probability of transportation of COVID-19 from Wuhan to 369 other cities in China before the quarantine. Expected COVID-19...
2019 novel coronavirus disease covid-19 China SARS-CoV-2 Wuhan coronavirus EPIDEMIOLOGY importation outbreak severe acute respiratory syndrome coronavirus 2 viruses Betacoronavirus covid-19 China Cities Coronavirus Infections Disease Outbreaks Forecasting Humans Models Statistical Pandemics Pneumonia Viral Quarantine Risk Assessment SARS-CoV-2 Stochastic Processes Transportation
Truancy and teenage pregnancy in English adolescent girls
ADOLESCENTS sexual behaviour social determinants teenage pregnancy truancy young people Adolescent Adolescent Behavior Adult England Female Humans Logistic Models Pregnancy Pregnancy in Adolescence Prospective Studies Psychology Educational ROC Curve Risk-Taking Schools Sexual Behavior Social Problems Socioeconomic Factors Students Young Adult
Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care
Abstract: Bladder and kidney cancer are the 10th and 7th most common cancers in the United Kingdom (UK). They present with symptoms that are typically investigated via the same diagnostic pathway. However, diagnosing these...
Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance.
Yuehui Zhang, Min Hu, Fan Yang, Yizhuo Zhang, Shuting Ma, Dongqi Zhang, Xu Wang, Amanda Nancy Sferruzzi-Perri, Xiaoke Wu, Mats Brännström, Linus R Shao, Håkan Billig
Sep 21, 2021
Androgen receptor Flutamide Implantation Mitochondrial function POLYCYSTIC OVARY SYNDROME Pregnant uterus Androgens Animals Decidua Dihydrotestosterone Embryo Implantation Endometrium Female Hyperandrogenism Insulin Insulin Resistance Male Mitochondria POLYCYSTIC OVARY SYNDROME Pregnancy Rats Rats Sprague-Dawley Receptors Androgen Uterus
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Temo Barwari, Seda Eminaga, Ursula Mayr, Ruifang Lu, Paul C Armstrong, Melissa V Chan, Mahnaz Sahraei, Marta Fernández-Fuertes, Thomas Moreau, Javier Barallobre-Barreiro, Marc Lynch, Xiaoke Yin, Christian Schulte, Ferheen Baig, Raimund Pechlaner, Sarah R Langley, Anna Zampetaki, Peter Santer, Martin Weger, Roberto Plasenzotti, Markus Schosserer, Johannes Grillari, Stefan Kiechl, Johann Willeit, Ajay M Shah, Cedric Ghevaert, Timothy D Warner, Carlos Fernández-Hernando, Yajaira Suárez, Manuel Mayr
Jan 09, 2019
Fibrosis is a major contributor to organ disease for which no specific therapy is available. MicroRNA-21 (miR-21) has been implicated in the fibrogenetic response, and inhibitors of miR-21 are currently undergoing clinical...
Cardiology Cell Biology Fibrosis NONCODING RNAS platelets Aged Aged 80 and over Animals Blood Platelets Clinical Trials as Topic Extracellular Matrix Female FIBROBLASTS Fibrosis Humans Male Mice Mice Inbred C57BL MicroRNAs Middle Aged Myocardium Prospective Studies Proteomics RNA Untranslated Transforming Growth Factor beta1 Wiskott-Aldrich Syndrome Protein
Are all regulatory compliant independent director appointments the same? An analysis of Taiwanese board appointments
Globally many regulators adopted a rules-based approach to independent director appointments stipulating ‘independence’ criteria. This paper investigates whether partitioning a regulatory compliant sample of independent director...
Corporate governance Entrenchment Incentive alignment Independent directors performance Taiwan /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/2000/2003 name=Finance /dk/atira/pure/subjectarea/asjc/2000/2002 name=Economics and Econometrics /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's...
Are all regulatory compliant independent director appointments the same? An analysis of Taiwanese board appointments
Globally many regulators adopted a rules-based approach to independent director appointments stipulating ‘independence’ criteria. This paper investigates whether partitioning a regulatory compliant sample of independent director...
Corporate governance Entrenchment Incentive alignment Independent directors performance Taiwan /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/2000/2003 name=Finance /dk/atira/pure/subjectarea/asjc/2000/2002 name=Economics and Econometrics /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management
Emerging Auditory Selectivity in the Caudomedial Neostriatum of the Zebra Finch Songbird
Caroline Wan-Yin Ang
Jan 01, 0001
The ability to identify and interpret auditory stimuli from the environmental milieu is of particular importance in species that communicate using learned vocalizations. By chronically recording multiunit neuronal responses in...
Published by: Rockefeller University
Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care.
Bladder and kidney cancer are the 10th and 7th most common cancers in the United Kingdom (UK). They present with symptoms that are typically investigated via the same diagnostic pathway. However, diagnosing these cancers can be...
Photorealistic Audio-driven Video Portraits
Video portraits are common in a variety of applications, such as videoconferencing, news broadcasting, and virtual education and training. We present a novel method to synthesize photorealistic video portraits for an input...
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient’s...
Development of a methodology for understanding the potency of risk connectivity
The Strategic Risk Register System (SRRS) is proposed by the writers as a practical methodology to enable the connectivity of risks to be elicited and evaluated so that the most potent risks in a system can be identified. The...
Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population
Relightable Detailed Human Reconstruction from Sparse Flashlight Images
We present a lightweight system for reconstructing human geometry and appearance from sparse flashlight images. Our system produces detailed geometry including garment wrinkles and surface reflectance, which are exportable...
Human reconstruction human relighting neural implicit field sparse view reconstruction /dk/atira/pure/subjectarea/asjc/1700/1712 name=Software /dk/atira/pure/subjectarea/asjc/1700/1711 name=Signal Processing /dk/atira/pure/subjectarea/asjc/1700/1707 name=Computer Vision and Pattern Recognition /dk/atira/pure/subjectarea/asjc/1700/1704 name=Computer Graphics and Computer-Aided Design
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