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Results: 1129
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Feb 09, 2023
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Mar 07, 2023
Modular polyketide synthase (PKS) is an ingenious core machine that catalyzes abundant polyketides in nature. Exploring interactions among modules in PKS is very important for understanding the overall biosynthetic process and...
Published by: Nature Communications
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models.
Lindsay McMurray, Jennifer A Macdonald, Nisha Kuzhuppilly Ramakrishnan, Yanyan Zhao, David W Williamson, Ole Tietz, Xiaoyun Zhou, Steven Kealey, Steven G Fagan, Tomáš Smolek, Veronika Cubinkova, Norbert Žilka, Maria Grazia Spillantini, Aviva M Tolkovsky, Michel Goedert, Franklin I Aigbirhio
Feb 16, 2021
Aggregated tau protein is a core pathology present in several neurodegenerative diseases. Therefore, the development and application of positron emission tomography (PET) imaging radiotracers that selectively bind to aggregated...
Comparative analysis of sequencing technologies for single-cell transcriptomics.
Kedar Nath Natarajan, Zhichao Miao, Miaomiao Jiang, Xiaoyun Huang, Hongpo Zhou, Jiarui Xie, Chunqing Wang, Shishang Qin, Zhikun Zhao, Liang Wu, Naibo Yang, Bo Li, Yong Hou, Shiping Liu, Sarah A Teichmann
May 16, 2019
Single-cell RNA-seq technologies require library preparation prior to sequencing. Here, we present the first report to compare the cheaper BGISEQ-500 platform to the Illumina HiSeq platform for scRNA-seq. We generate a resource...
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells.
Xiaoyun Zhang, Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Shankar Balasubramanian
Aug 02, 2021
DNA-protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we...
Published by: Nature chemistry
Promoter G-quadruplex folding precedes transcription and is controlled by chromatin.
Jiazhen Shen, Dhaval Varshney, Angela Simeone, Xiaoyun Zhang, Santosh Adhikari, David Tannahill, Shankar Balasubramanian
Apr 13, 2021
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
Harmonic Analyses of Hydrodynamic Characteristics for Gap Resonance Between Fixed Box and Vertical Wall
Two marine structures arranged side by side with a narrow gap may suffer from violent free-surface resonance, which would cause green water on deck, dramatically raise hydrodynamic loads on structures and seriously threaten...
Gap resonance harmonic analyses OpenFOAM® resonant wave height Wave loads /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.
Maria Grandoch, Ulrich Flögel, Sam Virtue, Julia K Maier, Tomas Jelenik, Christina Kohlmorgen, Kathrin Feldmann, Yanina Ostendorf, Tamara R Castañeda, Zhou Zhou, Yu Yamaguchi, Emmani BM Nascimento, Vivekananda G Sunkari, Christine Goy, Martina Kinzig, Fritz Sörgel, Paul L Bollyky, Patrick Schrauwen, Hadi Al-Hasani, Michael Roden, Susanne Keipert, Antonio Vidal-Puig, Martin Jastroch, Judith Haendeler, Jens W Fischer
Oct 09, 2020
Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which...
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Yang Song, Thomas CT Michaels, Qingming Ma, Zhou Liu, Hao Yuan, Shuichi Takayama, Tuomas PJ Knowles, Ho Cheung Shum
Sep 29, 2018
Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that...
Harmonic Analyses of Hydrodynamic Characteristics for Gap Resonance Between Fixed Box and Vertical Wall
Two marine structures arranged side by side with a narrow gap may suffer from violent free-surface resonance, which would cause green water on deck, dramatically raise hydrodynamic loads on structures and seriously threaten...
Gap resonance harmonic analyses OpenFOAM® resonant wave height Wave loads /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water
Autocalibration of accelerometer data for free-living physical activity assessment using local gravity and temperature
Vincent T van Hees, Zhou Fang, Joss Langford, Felix Assah, Anwar Mohammad, Inacio CM da Silva, Michael I Trenell, Tom White, Nicholas J Wareham, Søren Brage
Aug 22, 2014
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
Dan Zhao, Hai Hao Han, Ling Zhu, Fang Zhou Xu, Xing Yu Ma, Jia Li, Tony D. James, Yi Zang, Xiao Peng He, Chengyun Wang
Sep 20, 2021
With this research, we have developed two long-wavelength theranostic probes (DCMT and DCMC) with aggregation-induced emission (AIE)-based properties for image-guided photodynamic therapy (PDT) of hepatoma cells. Introduction...
aggregation-induced emission (AIE) Mitochondria photodynamic therapy (PDT) photosensitizer theranostic probe /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
Dan Zhao, Hai Hao Han, Ling Zhu, Fang Zhou Xu, Xing Yu Ma, Jia Li, Tony D. James, Yi Zang, Xiao Peng He, Chengyun Wang
Sep 20, 2021
With this research, we have developed two long-wavelength theranostic probes (DCMT and DCMC) with aggregation-induced emission (AIE)-based properties for image-guided photodynamic therapy (PDT) of hepatoma cells. Introduction...
aggregation-induced emission (AIE) Mitochondria photodynamic therapy (PDT) photosensitizer theranostic probe /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Mirror-symmetric microtubule assembly and cell interactions drive lumen formation in the zebrafish neural rod.
Clare E Buckley, Xiaoyun Ren, Laura C Ward, Gemma C Girdler, Claudio Araya, Mary J Green, Brian S Clark, Brian A Link, Jonathan DW Clarke
Feb 01, 2019
By analysing the cellular and subcellular events that occur in the centre of the developing zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen formation. Cells from each side of the...
Animals Body Patterning Carrier Proteins Cell Communication Cell Division Cell Movement Cell Polarity Embryo Nonmammalian Green Fluorescent Proteins Luminescent Agents Microtubules Mutation Neural Tube Neurulation Nocodazole Protein Transport Recombinant Fusion Proteins Tubulin Modulators Zebrafish Zebrafish Proteins rab GTP-Binding Proteins
Logistics Distribution Route Optimization With Time Windows Based on Multi-Agent Deep Reinforcement Learning
Multi-depot vehicle routing problem with time windows (MDVRPTW) is a valuable practical issue in urban logistics. However, heuristic methods may fail to generate high-quality solutions for massive problems instantly. Thus, this...
Published by: IGI Global Scientific Publishing
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