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Research on the allocation efficiency and influencing factors of scientific and technological resources in the yangtze river delta city group
YH Cao, JX You, YJ Shi, W Hu
Jul 28, 2021
Through the establishment of a comprehensive evaluation index system, this paper analyzes the allocation of science and technology resources in the Yangtze River Delta urban agglomeration from 2014 to 2020, evaluates the...
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Designed beta-hairpins inhibit LDH5 oligomerization and enzymatic activity
Lactate dehydrogenase 5 (LDH5) is overexpressed in aggressive and metastatic tumors and is an attractive target for anticancer therapy. Small molecule drugs have been developed to target the substrate and/or the cofactor sites...
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Designed beta-hairpins inhibit LDH5 oligomerization and enzymatic activity
Lactate dehydrogenase 5 (LDH5) is overexpressed in aggressive and metastatic tumors and is an attractive target for anticancer therapy. Small molecule drugs have been developed to target the substrate and/or the cofactor sites...
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Development of a sensitive multiplexed open circuit potential system for the detection of prostate cancer biomarkers

We report the development of a sensitive label-free, cost-effective detection system with simultaneous multi-channel measurement of open circuit potential (OCP) variations for the detection of prostate specific antigen (PSA)....

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Development of a sensitive multiplexed open circuit potential system for the detection of prostate cancer biomarkers

We report the development of a sensitive label-free, cost-effective detection system with simultaneous multi-channel measurement of open circuit potential (OCP) variations for the detection of prostate specific antigen (PSA)....

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Stabilizing multiple topological fermions on a quantum computer
JM Koh, T Tai, YH Phee, WE Ng, CH Lee
Feb 16, 2022
AbstractIn classical and single-particle settings, non-trivial band topology always gives rise to robust boundary modes. For quantum many-body systems, however, multiple topological fermions are...
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Multimodal electrochemical and nanoplasmonic biosensors using ferrocene crowned nanoparticles for kinase drug discovery applications
The use of on-chip multimodal sensing approaches is very promising towards integrated biosensing systems, which measure different parameters involved in biomolecular interactions and provide automated validation of true...
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Multimodal electrochemical and nanoplasmonic biosensors using ferrocene crowned nanoparticles for kinase drug discovery applications
The use of on-chip multimodal sensing approaches is very promising towards integrated biosensing systems, which measure different parameters involved in biomolecular interactions and provide automated validation of true...
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First-Principles Dynamics of Fluorine Adsorption on Clean and Monohydrogenated Si{001}.
The interaction of highly reactive species with solid surfaces can result in modes of adsorption quite distinct from the classic molecular and dissociative events that are usually thought to dominate. For instance, compelling...
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Shear transformation zone analysis of anelastic relaxation of a metallic glass reveals distinct properties of α and β relaxations.
Metallic glasses with pronounced high-frequency β relaxation in their dynamic-mechanical response have been observed to exhibit large plasticity. Due to their disordered atomic structure, it is challenging to identify the...
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Top-down, bottom-up, or both? Toward an integrative perspective on operations strategy formation
YH Kim, FJ Sting, CH Loch
Sep 29, 2014
Operations strategy is formed via complex processes that transpire in multiple directions at multiple organizational levels. While most previous studies focus on the “macro-level” process of strategy formation from the dominant...
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Dielectric films for high performance capacitive energy storage

Dielectric capacitors are fundamental components in electronic and electrical systems due to their high-rate charging/discharging character and ultrahigh power density. Film dielectrics possess larger breakdown strength and...

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DEFLATE compression algorithm corrects for overestimation of phylogenetic diversity by Grantham approach to single-nucleotide polymorphism classification.
Improvements in speed and cost of genome sequencing are resulting in increasing numbers of novel non-synonymous single nucleotide polymorphisms (nsSNPs) in genes known to be associated with disease. The large number of nsSNPs...
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