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Results: 28
An evaluation tool kit of air quality micro-sensing units.
B Fishbain, U Lerner, N Castell, T Cole-Hunter, O Popoola, DM Broday, TM Iñiguez, M Nieuwenhuijsen, M Jovasevic-Stojanovic, D Topalovic, RL Jones, KS Galea, Y Etzion, F Kizel, YN Golumbic, A Baram-Tsabari, T Yacobi, D Drahler, JA Robinson, D Kocman, M Horvat, V Svecova, A Arpaci, A Bartonova
Jun 08, 2017
Executive function and high ambiguity perceptual discrimination contribute to individual differences in mnemonic discrimination in older adults.
Mnemonic discrimination deficits, or impaired ability to discriminate between similar events in memory, is a hallmark of cognitive aging, characterised by a stark age-related increase in false recognition. While individual...
A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population
Tammy YN Tong, Albert Koulman, Julian L Griffin, Nicholas J Wareham, Nita G Forouhi, Fumiaki Imamura
Oct 01, 2019
Mediterranean diet Acylcarnitines Amines Biomarkers dietary pattern Metabolomics molecular epidemiology Nutritional epidemiology Phospholipids sphingolipids Adult Biomarkers Diet Mediterranean Female Homeostasis Humans Insulin Resistance Lipid Metabolism Male Middle Aged Patient Compliance United Kingdom
AlN/CrN multilayer structures with increased thermal stability
CrAlYN nanolayered coatings of greatly enhanced thermal stability have been developed by doping with levels of Y up to 9 at.%. This prevented the complete dissolution of the layered structure after annealing at 1100 °C in Ar for...
Opportunities and Limitations of Mobile Neuroimaging Technologies in Educational Neuroscience.
Dietary cost associated with adherence to the Mediterranean diet, and its variation by socio-economic factors in the UK Fenland Study.
Tammy YN Tong, Fumiaki Imamura, Pablo Monsivais, Søren Brage, Simon J Griffin, Nicholas J Wareham, Nita G Forouhi
Feb 16, 2018
High cost of healthy foods could be a barrier to healthy eating. We aimed to examine the association between dietary cost and adherence to the Mediterranean diet in a non-Mediterranean country. We evaluated cross-sectional data...
MDS Mediterranean diet score Dietary cost Mediterranean diet socio-economic status Adult Animals Costs and Cost Analysis Cross-Sectional Studies Diet Healthy Diet Mediterranean Female Fishes Fruit Health Behavior Humans Male Meat Middle Aged Patient Compliance seafood Socioeconomic Factors United Kingdom Vegetables
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Mar 15, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Coupling Postsynthetic High-Temperature Oxidative Thermolysis and Thermal Rearrangements in Isoreticular Zinc MOFs
Timothy A. Ablott, Rhian Webby, Daniel R. Jenkinson, Alexandra Nikolich, Lujia Liu, Harina Amer Hamzah, Mary F. Mahon, Andrew D. Burrows, Christopher Richardson
Jan 17, 2022
Herein, we report coupling in situ high temperature postsynthetic modifications (PSMs) in metal–organic frameworks (MOFs). Thermo-reactive propargyloxy-functionalized zinc IRMOFs (isoreticular metal–organic frameworks)...
Coupling Postsynthetic High-Temperature Oxidative Thermolysis and Thermal Rearrangements in Isoreticular Zinc MOFs
Timothy A. Ablott, Rhian Webby, Daniel R. Jenkinson, Alexandra Nikolich, Lujia Liu, Harina Amer Hamzah, Mary F. Mahon, Andrew D. Burrows, Christopher Richardson
Jan 17, 2022
Herein, we report coupling in situ high temperature postsynthetic modifications (PSMs) in metal–organic frameworks (MOFs). Thermo-reactive propargyloxy-functionalized zinc IRMOFs (isoreticular metal–organic frameworks)...
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Jan 22, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity
Sofia Christakoudi, Konstantinos K Tsilidis, David C Muller, Heinz Freisling, Elisabete Weiderpass, Kim Overvad, Stefan Söderberg, Christel Häggström, Tobias Pischon, Christina C Dahm, Jie Zhang, Anne Tjønneland, Jytte Halkjaer, Conor MacDonald, Marie-Christine Boutron-Ruault, Francesca Romana Mancini, Tilman Kühn, Rudolf Kaaks, Matthias B Schulze, Antonia Trichopoulou, Anna Karakatsani, Eleni Peppa, Giovanna Masala, Valeria Pala, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, J Ramón Quirós, Antonio Agudo, Maria-Jose Sánchez, Lluís Cirera, Aurelio Barricarte-Gurrea, Pilar Amiano, Ensieh Memarian, Emily Sonestedt, Bas Bueno-de-Mesquita, Anne M May, Kay-Tee Khaw, Nicholas J Wareham, Tammy YN Tong, Inge Huybrechts, Hwayoung Noh, Elom K Aglago, Merete Ellingjord-Dale, Heather A Ward, Dagfinn Aune, Elio Riboli
Nov 02, 2020
Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index...
Blood polyphenol concentrations and differentiated thyroid carcinoma in women from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Raul Zamora-Ros, Leila Lujan-Barroso, David Achaintre, Silvia Franceschi, Cecilie Kyrø, Kim Overvad, Anne Tjønneland, Therese Truong, Lucie Lecuyer, Marie-Christine Boutron-Ruault, Verena Katzke, Theron S Johnson, Matthias B Schulze, Antonia Trichopoulou, Eleni Peppa, Carlo La Vechia, Giovanna Masala, Valeria Pala, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Guri Skeie, J Ramón Quirós, Miguel Rodriguez-Barranco, Pilar Amiano, María-Dolores Chirlaque, Eva Ardanaz, Martin Almquist, Joakim Hennings, Roel Vermeulen, Nicholas J Wareham, Tammy YN Tong, Dagfinn Aune, Graham Byrnes, Elisabete Weiderpass, Augustin Scalbert, Sabina Rinaldi, Antonio Agudo
Nov 17, 2020
BACKGROUND: Polyphenols are natural compounds with anticarcinogenic properties in cellular and animal models, but epidemiological evidence determining the associations of these compounds with thyroid cancer (TC) is lacking....
Glycemic index, glycemic load, and risk of coronary heart disease
Sabina Sieri, Claudia Agnoli, Sara Grioni, Elisabete Weiderpass, Amalia Mattiello, Ivonne Sluijs, Maria Jose Sanchez, Marianne Uhre Jakobsen, Michael Sweeting, Yvonne T van der Schouw, Lena Maria Nilsson, Patrik Wennberg, Verena A Katzke, Tilman Kühn, Kim Overvad, Tammy YN Tong, Moreno-Iribas Conchi, José Ramón Quirós, Juan Manuel García-Torrecillas, Olatz Mokoroa, Jesús-Humberto Gómez, Anne Tjønneland, Emiliy Sonestedt, Antonia Trichopoulou, Anna Karakatsani, Elissavet Valanou, Jolanda MA Boer, WM Monique Verschuren, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Anne-Laure Madika, Manuela M Bergmann, Matthias B Schulze, Pietro Ferrari, Heinz Freisling, Hannah Lennon, Carlotta Sacerdote, Giovanna Masala, Rosario Tumino, Elio Riboli, Nicholas J Wareham, John Danesh, Nita G Forouhi, Adam S Butterworth, Vittorio Krogh
Jun 09, 2020
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.
Charles C Bell, Katie A Fennell, Yih-Chih Chan, Florian Rambow, Miriam M Yeung, Dane Vassiliadis, Luis Lara, Paul Yeh, Luciano G Martelotto, Aljosja Rogiers, Brandon E Kremer, Olena Barbash, Helai P Mohammad, Timothy M Johanson, Marian L Burr, Arindam Dhar, Natalie Karpinich, Luyi Tian, Dean S Tyler, Laura MacPherson, Junwei Shi, Nathan Pinnawala, Chun Yew Fong, Anthony T Papenfuss, Sean M Grimmond, Sarah-Jane Dawson, Rhys S Allan, Ryan G Kruger, Christopher R Vakoc, David L Goode, Shalin H Naik, Omer Gilan, Enid YN Lam, Jean-Christophe Marine, Rab K Prinjha, Mark A Dawson
Aug 21, 2019
Non-genetic drug resistance is increasingly recognised in various cancers. Molecular insights into this process are lacking and it is unknown whether stable non-genetic resistance can be overcome. Using single cell...
Animals Antineoplastic Agents Bone Marrow CRISPR-Cas Systems Cell Line Tumor Drug Resistance Neoplasm Epigenesis Genetic Female Gene Expression Regulation Leukemic HEK293 Cells Humans Kaplan-Meier Estimate Leukemia Myeloid Acute Mice Mice Inbred C57BL Sequence Analysis RNA Single-Cell Analysis Trans-Activators Transcription Genetic Treatment Outcome Xenograft Model Antitumor Assays
Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations.
Franziska Jannasch, Janine Kröger, Claudia Agnoli, Aurelio Barricarte, Heiner Boeing, Valerie Cayssials, Sandra Colorado-Yohar, Christina C Dahm, Courtney Dow, Guy Fagherazzi, Paul W Franks, Heinz Freisling, Marc J Gunter, Nicola D Kerrison, Timothy J Key, Kay-Tee Khaw, Tilman Kühn, Cecilie Kyro, Francesca Romana Mancini, Olatz Mokoroa, Peter Nilsson, Kim Overvad, Domenico Palli, Salvatore Panico, Jose Ramón Quirós García, Olov Rolandsson, Carlotta Sacerdote, Mariá-José Sánchez, Mohammad Sediq Sahrai, Ruth Schübel, Ivonne Sluijs, Annemieke MW Spijkerman, Anne Tjonneland, Tammy YN Tong, Rosario Tumino, Elio Riboli, Claudia Langenberg, Stephen J Sharp, Nita G Forouhi, Matthias B Schulze, Nicholas J Wareham
Feb 22, 2019
diet-disease association dietary patterns Meta-Analysis principal component analysis replication type 2 diabetes mellitus Adult Aged Case-Control Studies Cohort Studies Diabetes mellitus Type 2 Diet Disease Susceptibility Europe Feasibility Studies Female Humans Incidence Male Middle Aged principal component analysis Risk Factors
Blood pressure and risk of cancer in the European Prospective Investigation into Cancer and Nutrition.
Sofia Christakoudi, Artemisia Kakourou, Georgios Markozannes, Ioanna Tzoulaki, Elisabete Weiderpass, Paul Brennan, Marc Gunter, Christina C Dahm, Kim Overvad, Anja Olsen, Anne Tjønneland, Marie-Christine Boutron-Ruault, Anne-Laure Madika, Gianluca Severi, Verena Katzke, Tilman Kühn, Manuela M Bergmann, Heiner Boeing, Anna Karakatsani, Georgia Martimianaki, Paschalis Thriskos, Giovanna Masala, Sabina Sieri, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Antonio Agudo, Daniel Redondo-Sánchez, Sandra M Colorado-Yohar, Olatz Mokoroa, Olle Melander, Tanja Stocks, Christel Häggström, Sophia Harlid, Bas Bueno-de-Mesquita, Carla H van Gils, Roel CH Vermeulen, Kay-Tee Khaw, Nicholas J Wareham, Tammy YN Tong, Heinz Freisling, Mattias Johansson, Hannah Lennon, Dagfinn Aune, Elio Riboli, Dimitrios Trichopoulos, Antonia Trichopoulou, Konstantinos K Tsilidis
Jul 22, 2019
Several studies have reported associations of hypertension with cancer, but not all results were conclusive. We examined the association of systolic (SBP) and diastolic (DBP) blood pressure with the development of incident...
Biological material collection to advance translational research and treatment of children with CNS tumours
Stefan Rutkowski, Piergiorgio Modena, Daniel Williamson, Kornelius Kerl, Karsten Nysom, Barry Pizer, Ute Bartels, Stephanie Puget, François Doz, Antony Michalski, Katja von Hoff, Mathilde Chevignard, Shivaram Avula, Matthew J Murray, Stefan Schönberger, Thomas Czech, Antoinette YN Schouten-van Meeteren, Uwe Kordes, Christof M Kramm, Dannis G van Vuurden, Esther Hulleman, Geert O Janssens, Guirish A Solanki, Marie-Luise C van Veelen, Ulrich Thomale, Martin U Schuhmann, Chris Jones, Felice Giangaspero, Dominique Figarella-Branger, Torsten Pietsch, Steve C Clifford, Stefan M Pfister, Stefaan W Van Gool
Feb 15, 2019
Paediatric CNS tumours are the most common cause of childhood cancer-related morbidity and mortality, and improvements in their diagnosis and treatment are needed. New genetic and epigenetic information about paediatric CNS...
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations
Ju-Sheng Zheng, Jian'an Luan, Eleni Sofianopoulou, Stephen J Sharp, Felix R Day, Fumiaki Imamura, Thomas E Gundersen, Luca A Lotta, Ivonne Sluijs, Isobel D Stewart, Rupal L Shah, Yvonne T van der Schouw, Eleanor Wheeler, Eva Ardanaz, Heiner Boeing, Miren Dorronsoro, Christina C Dahm, Niki Dimou, Douae El-Fatouhi, Paul W Franks, Guy Fagherazzi, Sara Grioni, José María Huerta, Alicia K Heath, Louise Hansen, Mazda Jenab, Paula Jakszyn, Rudolf Kaaks, Tilman Kühn, Kay-Tee Khaw, Nasser Laouali, Giovanna Masala, Peter M Nilsson, Kim Overvad, Anja Olsen, Salvatore Panico, J Ramón Quirós, Olov Rolandsson, Miguel Rodríguez-Barranco, Carlotta Sacerdote, Annemieke MW Spijkerman, Tammy YN Tong, Rosario Tumino, Konstantinos K Tsilidis, John Danesh, Elio Riboli, Adam S Butterworth, Claudia Langenberg, Nita G Forouhi, Nicholas J Wareham
Sep 17, 2020
BACKGROUND: Prior research suggested a differential association of 25-hydroxyvitamin D (25(OH)D) metabolites with type 2 diabetes (T2D), with total 25(OH)D and 25(OH)D3 inversely associated with T2D, but the epimeric form...
Estimated Substitution of Tea or Coffee for Sugar-Sweetened Beverages Was Associated with Lower Type 2 Diabetes Incidence in Case-Cohort Analysis across 8 European Countries in the EPIC-InterAct Study.
Fumiaki Imamura, Matthias B Schulze, Stephen J Sharp, Marcela Guevara, Dora Romaguera, Benedetta Bendinelli, Elena Salamanca-Fernández, Eva Ardanaz, Larraitz Arriola, Dagfinn Aune, Heiner Boeing, Courtney Dow, Guy Fagherazzi, Paul W Franks, Heinz Freisling, Paula Jakszyn, Rudolf Kaaks, Kay-Tee Khaw, Tilman Kühn, Francesca R Mancini, Giovanna Masala, Maria-Dolores Chirlaque, Peter M Nilsson, Kim Overvad, Valeria M Pala, Salvatore Panico, Aurora Perez-Cornago, Jose R Quirós, Fulvio Ricceri, Miguel Rodríguez-Barranco, Olov Rolandsson, Ivonne Sluijs, Magdalena Stepien, Annemieke MW Spijkerman, Anne Tjønneland, Tammy YN Tong, Rosario Tumino, Linda ET Vissers, Heather A Ward, Claudia Langenberg, Elio Riboli, Nita G Forouhi, Nick J Wareham
Jun 20, 2019
Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes
Ju-Sheng Zheng, Stephen J Sharp, Fumiaki Imamura, Rajiv Chowdhury, Thomas E Gundersen, Marinka Steur, Ivonne Sluijs, Yvonne T van der Schouw, Antonio Agudo, Dagfinn Aune, Aurelio Barricarte, Heiner Boeing, María-Dolores Chirlaque, Miren Dorronsoro, Heinz Freisling, Douae El-Fatouhi, Paul W Franks, Guy Fagherazzi, Sara Grioni, Marc J Gunter, Cecilie Kyrø, Verena Katzke, Tilman Kühn, Kay-Tee Khaw, Nasser Laouali, Giovanna Masala, Peter M Nilsson, Kim Overvad, Salvatore Panico, Keren Papier, J Ramón Quirós, Olov Rolandsson, Daniel Redondo-Sánchez, Fulvio Ricceri, Matthias B Schulze, Annemieke MW Spijkerman, Anne Tjønneland, Tammy YN Tong, Rosario Tumino, Elisabete Weiderpass, John Danesh, Adam S Butterworth, Elio Riboli, Nita G Forouhi, Nicholas J Wareham
May 20, 2020
Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases
Heinz Freisling, Vivian Viallon, Hannah Lennon, Vincenzo Bagnardi, Cristian Ricci, Adam S Butterworth, Michael Sweeting, David Muller, Isabelle Romieu, Pauline Bazelle, Marina Kvaskoff, Patrick Arveux, Gianluca Severi, Christina Bamia, Tilman Kühn, Rudolf Kaaks, Manuela Bergmann, Heiner Boeing, Anne Tjønneland, Anja Olsen, Kim Overvad, Christina C Dahm, Virginia Menéndez, Antonio Agudo, Maria-Jose Sánchez, Pilar Amiano, Carmen Santiuste, Aurelio Barricarte Gurrea, Tammy YN Tong, Julie A Schmidt, Ioanna Tzoulaki, Konstantinos K Tsilidis, Heather Ward, Domenico Palli, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Salvatore Panico, H Susan J Picavet, Marije Bakker, Evelyn Monninkhof, Peter Nilsson, Jonas Manjer, Olov Rolandsson, Elin Thysell, Elisabete Weiderpass, Mazda Jenab, Elio Riboli, Paolo Vineis, John Danesh, Nick J Wareham, Marc J Gunter, Pietro Ferrari
Jan 29, 2020
BACKGROUND: Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely...
Cancer Cancer and cardiometabolic multimorbidity cardiovascular disease Diabetes Healthy lifestyle obesity Prevention Adult Alcohol Drinking Body Mass Index Cardiovascular Diseases Cohort Studies Diabetes mellitus Type 2 Female Humans Incidence Life Style Male Middle Aged multimorbidity Neoplasms Proportional Hazards Models Prospective Studies Risk Factors Risk Reduction Behavior
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer.
Marian L Burr, Christina E Sparbier, Kah Lok Chan, Yih-Chih Chan, Ariena Kersbergen, Enid YN Lam, Elizabeth Azidis-Yates, Dane Vassiliadis, Charles C Bell, Omer Gilan, Susan Jackson, Lavinia Tan, Stephen Q Wong, Sebastian Hollizeck, Ewa M Michalak, Hannah V Siddle, Michael T McCabe, Rab K Prinjha, Glen R Guerra, Benjamin J Solomon, Shahneen Sandhu, Sarah-Jane Dawson, Paul A Beavis, Richard W Tothill, Carleen Cullinane, Paul J Lehner, Kate D Sutherland, Mark A Dawson
Aug 29, 2019
EZH2 MHC class I Antigen Presentation bivalency Cancer Epigenetic Repression HISTONE METHYLTRANSFERASE Immune Evasion Immunotherapy polycomb Animals Antigen Presentation Antineoplastic Agents Immunological Antineoplastic Combined Chemotherapy Protocols Cell Line Tumor DNA Methylation Down-Regulation Drug Resistance Neoplasm Epigenetic Repression Female Gene Expression Regulation Neoplastic Histocompatibility Antigens Class I Histone Code Humans Mice Middle Aged Neoplasms Polycomb Repressive Complex 2 T-Lymphocytes Tumor Escape Xenograft Model Antitumor Assays
The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke
Tammy YN Tong, Paul N Appleby, Timothy J Key, Christina C Dahm, Kim Overvad, Anja Olsen, Anne Tjønneland, Verena Katzke, Tilman Kühn, Heiner Boeing, Anna Karakatsani, Eleni Peppa, Antonia Trichopoulou, Elisabete Weiderpass, Giovanna Masala, Sara Grioni, Salvatore Panico, Rosario Tumino, Jolanda MA Boer, WM Monique Verschuren, J Ramón Quirós, Antonio Agudo, Miguel Rodríguez-Barranco, Liher Imaz, María-Dolores Chirlaque, Conchi Moreno-Iribas, Gunnar Engström, Emily Sonestedt, Marcus Lind, Julia Otten, Kay-Tee Khaw, Dagfinn Aune, Elio Riboli, Nicholas J Wareham, Fumiaki Imamura, Nita G Forouhi, Emanuele Di Angelantonio, Angela M Wood, Adam S Butterworth, Aurora Perez-Cornago
Jan 13, 2020
Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations
Daniel B Ibsen, Marinka Steur, Fumiaki Imamura, Kim Overvad, Matthias B Schulze, Benedetta Bendinelli, Marcela Guevara, Antonio Agudo, Pilar Amiano, Dagfinn Aune, Aurelio Barricarte, Ulrika Ericson, Guy Fagherazzi, Paul W Franks, Heinz Freisling, Jose R Quiros, Sara Grioni, Alicia K Heath, Inge Huybrechts, Verena Katze, Nasser Laouali, Francesca Mancini, Giovanna Masala, Anja Olsen, Keren Papier, Stina Ramne, Olov Rolandsson, Carlotta Sacerdote, Maria-José Sánchez, Carmen Santiuste, Vittorio Simeon, Annemieke MW Spijkerman, Bernard Srour, Anne Tjønneland, Tammy YN Tong, Rosario Tumino, Yvonne T van der Schouw, Elisabete Weiderpass, Clemens Wittenbecher, Stephen J Sharp, Elio Riboli, Nita G Forouhi, Nick J Wareham
Aug 07, 2020
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