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Anticonvulsant activities of α-asaronol ((E)-3'-hydroxyasarone), an active constituent derived from α-asarone.
Xirui He, Yajun Bai, Min Zeng, Zefeng Zhao, Qiang Zhang, Ning Xu, Fanggang Qin, Xiaoyang Wei, Meimei Zhao, Ni Wu, Zehua Li, Yajun Zhang, Tai-Ping Fan, Xiaohui Zheng
Feb 08, 2019
BACKGROUND: Epilepsy is one of chronic neurological disorders that affects 0.5-1.0% of the world's population during their lifetime. There is a still significant need to develop novel anticonvulsant drugs that possess superior...
Acute toxicity Anticonvulsant neurotoxicity α-asaronol 3-Mercaptopropionic Acid Allylbenzene Derivatives Animals Anisoles Anticonvulsants Brain Dioxolanes Disease Models Animal Dose-Response Relationship Drug electroshock Lethal Dose 50 Male Mice Motor Activity Neurotoxicity Syndromes Pentylenetetrazole Rotarod Performance Test Seizures
How the City of London lost at Brexit
HE Thompson
Aug 23, 2017
The nature of the City of London as an offshore financial centre has long made London dependent on the British state providing protection from external political regulation, even as London’s foreign currency business separated...
Diagnostics of Non-Maxwellian Electron Distributions in Solar Active Regions from Fe xii Lines Observed by the Hinode Extreme Ultraviolet Imaging Spectrometer and Interface Region Imaging Spectrograph
Abstract
We present joint Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) and Interface Region Imaging Spectrograph (IRIS) observations of Fe xii lines in...
Electronic stopping power in gold
The electronic stopping power of H and He moving through gold is obtained to high accuracy using time-evolving density-functional theory, thereby bringing usual first principles accuracies into this kind of strongly coupled...
Cournot oligopoly game-based local energy trading considering renewable energy uncertainty costs
Facilitated by advanced information and communication technologies (ICTs), local energy trading develops rapidly, playing an important role in the energy supply chain. Thus, it is essential to develop local trading models and...
Cournot game electric vehicles Energy storage Local energy trading price elasticity Renewable Energy Renewable uncertainty /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Route to high-energy density polymeric nitrogen t-N via He-N compounds.
Yinwei Li, Xiaolei Feng, Hanyu Liu, Jian Hao, Simon AT Redfern, Weiwei Lei, Dan Liu, Yanming Ma
Mar 16, 2018
Polymeric nitrogen, stabilized by compressing pure molecular nitrogen, has yet to be recovered to ambient conditions, precluding its application as a high-energy density material. Here we suggest a route for synthesis of a...
R-matrix Electron-impact Excitation Data for the H- and He-like Ions with Z = 6−30
Abstract
Plasma models built on extensive atomic data are essential to interpreting observed cosmic spectra. H-like Lyman series and He-like triplets observable in the X-ray band...
Cournot oligopoly game-based local energy trading considering renewable energy uncertainty costs
Facilitated by advanced information and communication technologies (ICTs), local energy trading develops rapidly, playing an important role in the energy supply chain. Thus, it is essential to develop local trading models and...
Cournot game electric vehicles Energy storage Local energy trading price elasticity Renewable Energy Renewable uncertainty /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Stokes drift through corals
We investigate the all-penetrating drift velocities, due to surface wave
motion in an effectively inviscid fluid that overlies a saturated porous bed of
finite depth. Previous work in this area either neglects the large-scale...
High-Commitment Work Systems and Employee Voice:
Purpose: Although scholars have suggested that employees often carefully consider social contexts before enacting voice, few studies have explored whether firms foster employee voice behavior by adopting a set of systematic...
High-Commitment Work Systems and Employee Voice:
Purpose: Although scholars have suggested that employees often carefully consider social contexts before enacting voice, few studies have explored whether firms foster employee voice behavior by adopting a set of systematic...
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
Xianzhi Chai, Hai Hao Han, Adam C. Sedgwick, Na Li, Yi Zang, Tony D. James, Junji Zhang, Xi Le Hu, Yang Yu, Yao Li, Yan Wang, Jia Li, Xiao Peng He, He Tian
Oct 21, 2020
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG, that was designed to prebind to human serum albumin (HSA) to form the probe/protein hybrid, NpG@HSA. The formation of NpG@HSA led to an...
/dk/atira/pure/subjectarea/asjc/1500/1503 name=Catalysis /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1500/1505 name=Colloid and Surface Chemistry /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
He Ala Kuikui Lima Kānaka
This article focuses on decolonizing, or specifically Indigenizing, a school of social work that has a stated focus on Native Hawaiians, other Pacific Islanders, and Asian populations in the Pacific region. Armed with Kanaka...
Published by: Memorial University of Newfoundland
‘No One Knows What He is Until He is Told’
Ruth Watson
Mar 07, 2016
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
Xianzhi Chai, Hai Hao Han, Adam C. Sedgwick, Na Li, Yi Zang, Tony D. James, Junji Zhang, Xi Le Hu, Yang Yu, Yao Li, Yan Wang, Jia Li, Xiao Peng He, He Tian
Oct 21, 2020
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG, that was designed to prebind to human serum albumin (HSA) to form the probe/protein hybrid, NpG@HSA. The formation of NpG@HSA led to an...
/dk/atira/pure/subjectarea/asjc/1500/1503 name=Catalysis /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1500/1505 name=Colloid and Surface Chemistry /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
SIRS Triggered by Acute Right Ventricular Function, Mimicked Septic Shock.
BACKGROUND: The systemic inflammatory response syndrome (SIRS) is a complex immune response which can be precipitated by non-infectious aetiologies such as trauma, burns or pancreatitis. Addressing the underlying cause is...
Biosynthesis of Putrescine from L-arginine Using Engineered Escherichia coli Whole Cells
Putrescine, a biogenic amine, is a highly valued compound in medicine, industry, and agriculture. In this study, we report a whole-cell biocatalytic method in Escherichia coli for the production of putrescine, using...
Interventions to increase physical activity in children 0-5 years old
OBJECTIVE: The objective of the study is to evaluate the effectiveness of interventions to increase physical activity (PA) in 0-5 year olds and to determine what works, for whom, in what circumstances. DESIGN: Systematic review...
Medical Imaging Biomarker Discovery and Integration Towards AI-Based Personalized Radiotherapy.
Intensity-modulated radiation therapy (IMRT) has been used for high-accurate physical dose distribution sculpture and employed to modulate different dose levels into Gross Tumor Volume (GTV), Clinical Target Volume (CTV) and...
Interval State Estimation in Active Distribution Systems Considering Multiple Uncertainties.
Distribution system state estimation (DSSE) plays a significant role for the system operation management and control. Due to the multiple uncertainties caused by the non-Gaussian measurement noise, inaccurate line parameters...
Towards Automated Detection of Higher-Order Command Injection Vulnerabilities in IoT Devices
Command injection vulnerabilities are among the most common and dangerous attack vectors in IoT devices. Current detection approaches can detect single-step injection vulnerabilities well by fuzzing tests. However, an attacker...
Published by: IGI Global Scientific Publishing
Tetrazine Carbon Nanotubes for Pretargeted In Vivo "Click-to-Release" Bioorthogonal Tumour Imaging.
The bioorthogonal inverse-electron-demand Diels-Alder (IEDDA) cleavage reaction between tetrazine and trans-cyclooctene (TCO) is a powerful way to control the release of bioactive agents and imaging probes. In this study, a...
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