4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.
Maria Grandoch,
Ulrich Flögel,
Sam Virtue,
Julia K Maier,
Tomas Jelenik,
Christina Kohlmorgen,
Kathrin Feldmann,
Yanina Ostendorf,
Tamara R Castañeda,
Zhou Zhou,
Yu Yamaguchi,
Emmani BM Nascimento,
Vivekananda G Sunkari,
Christine Goy,
Martina Kinzig,
Fritz Sörgel,
Paul L Bollyky,
Patrick Schrauwen,
Hadi Al-Hasani,
Michael Roden,
Susanne Keipert,
Antonio Vidal-Puig,
Martin Jastroch,
Judith Haendeler,
Jens W Fischer
Oct 09, 2020
Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which...