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Results: 27
Raynaud phenomenon and digital ulcers in systemic sclerosis
Michael Hughes, Yannick Allanore, Lorinda Chung, John D. Pauling, Christopher P. Denton, Marco Matucci-Cerinic
Apr 30, 2020
Raynaud phenomenon is a symptom complex caused by impaired digital perfusion and can occur as a primary phenomenon or secondary to a wide range of underlying causes. Raynaud phenomenon occurs in virtually all patients with...
Raynaud phenomenon and digital ulcers in systemic sclerosis
Michael Hughes, Yannick Allanore, Lorinda Chung, John D. Pauling, Christopher P. Denton, Marco Matucci-Cerinic
Apr 30, 2020
Raynaud phenomenon is a symptom complex caused by impaired digital perfusion and can occur as a primary phenomenon or secondary to a wide range of underlying causes. Raynaud phenomenon occurs in virtually all patients with...
Bubbling solutions for nonlocal elliptic problems
We investigate bubbling solutions for the nonlocal equationAsΩu=up, u>0in Ω,under homogeneous Dirichlet conditions, where Ω is a bounded and smooth domain. The operator AsΩ stands for two types of nonlocal operators that we...
Bubbling solutions for nonlocal elliptic problems
We investigate bubbling solutions for the nonlocal equationAsΩu=up, u>0in Ω,under homogeneous Dirichlet conditions, where Ω is a bounded and smooth domain. The operator AsΩ stands for two types of nonlocal operators that we...
The sharing of autobiographical memories elicits social support.
We examine whether and how the autobiographical memories that we share can influence the social support that people offer us. Study 1 examined whether sharing specific (e.g., I was upset when reading my expartner’s email last...
emotional support Episodic memory Instrumental support overgeneral memory specificity /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology
The complex null string, Galilean conformal algebra and scattering
equations
The scattering equation formalism for scattering amplitudes, and its stringy
incarnation, the ambitwistor string, remains a mysterious construction. In this
paper, we pursue the study a gauged-unfixed version of the ambitwistor...
The sharing of autobiographical memories elicits social support.
We examine whether and how the autobiographical memories that we share can influence the social support that people offer us. Study 1 examined whether sharing specific (e.g., I was upset when reading my expartner’s email last...
emotional support Episodic memory Instrumental support overgeneral memory specificity /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology
Impairment in karrikin but not strigolactone sensing enhances root skewing in Arabidopsis thaliana.
Stéphanie M Swarbreck, Yannick Guerringue, Elsa Matthus, Fiona JC Jamieson, Julia M Davies
Oct 23, 2019
Roots form highly complex systems varying in growth direction and branching pattern to forage for nutrients efficiently. Here mutations in the KAI2 (KARRIKIN INSENSITIVE) α/β-fold hydrolase and the MAX2 (MORE AXILLARY GROWTH 2)...
Arabidopsis thaliana karrikin ROOT skewing Strigolactone waving 4-Butyrolactone Arabidopsis Arabidopsis Proteins Carrier Proteins Furans Gene Expression Regulation Plant Hydrolases Intracellular Signaling Peptides and Proteins Lactones Mutation Phenotype Plant Growth Regulators Plant Roots Pyrans Signal Transduction Transcriptome
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD.
Yannick Marcon, Tom Bishop, Demetris Avraam, Xavier Escriba-Montagut, Patricia Ryser-Welch, Stuart Wheater, Paul Burton, Juan R González
Apr 09, 2021
Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and share...
Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19.
Julika Neumann, Teresa Prezzemolo, Lore Vanderbeke, Carlos P Roca, Margaux Gerbaux, Silke Janssens, Mathijs Willemsen, Oliver Burton, Pierre Van Mol, Yannick Van Herck, CONTAGIOUS co‐authors, Joost Wauters, Els Wauters, Adrian Liston, Stephanie Humblet-Baron
Jan 08, 2021
OBJECTIVES: The pandemic spread of the coronavirus SARS-CoV-2 is due, in part, to the immunological properties of the host-virus interaction. The clinical presentation varies from individual to individual, with asymptomatic...
Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation.
Charles J Underwood, Kyuha Choi, Christophe Lambing, Xiaohui Zhao, Heïdi Serra, Filipe Borges, Joe Simorowski, Evan Ernst, Yannick Jacob, Ian R Henderson, Robert A Martienssen
Jun 04, 2018
Eukaryotic centromeres contain the kinetochore, which connects chromosomes to the spindle allowing segregation. During meiosis, centromeres are suppressed for inter-homolog crossover, as recombination in these regions can cause...
Impact of cholesterol on proinflammatory monocyte production by the bone marrow.
Lotte CA Stiekema, Lisa Willemsen, Yannick Kaiser, Koen HM Prange, Nicholas J Wareham, S Matthijs Boekholdt, Carlijn Kuijk, Menno PJ de Winther, Carlijn Voermans, Matthias Nahrendorf, Erik SG Stroes, Jeffrey Kroon
Aug 16, 2021
AIM: Preclinical work indicates that low-density lipoprotein cholesterol (LDL-C) not only drives atherosclerosis by directing the innate immune response at plaque level but also augments proinflammatory monocyte production in...
Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane.
Vinaya Phatak, Yannick von Grabowiecki, Justyna Janus, Leah Officer, Caron Behan, Lydia Aschauer, Lucia Pinon, Hannah Mackay, Sara Zanivan, Jim C Norman, Michael Kelly, John Le Quesne, Patricia AJ Muller
Feb 24, 2021
TP53 is the most frequently mutated gene in cancers. Mutations lead to loss of p53 expression or expression of a mutant protein. Mutant p53 proteins commonly lose wild-type function, but can also acquire novel functions in...
ATP Binding Cassette Transporter Subfamily B Adaptor Proteins Signal Transducing Animals Antineoplastic Agents Cell Membrane cisplatin Dose-Response Relationship Drug Drug Resistance Neoplasm Etoposide HCT116 Cells Humans Male Membrane Proteins Mice Inbred BALB C Mice Nude Mutation Neoplasms Tumor Burden Tumor Suppressor Protein p53 Xenograft Model Antitumor Assays
The Impact of Digital Media on Urban Discourse
Carlos Mendez, Yannick Drijfhout, Virginia Arena, Lukasz Damurski, Paweł Pach, Kasia Piskorek
Jan 01, 2023
The media plays a crucial role in disseminating public information. This holds particular significance in urban contexts where it is vital for citizens to be informed about local issues as an integral element of urban discourse...
Published by: IGI Global Scientific Publishing
apoB/apoA-I Ratio and Lp(a) Associations With Aortic Valve Stenosis Incidence
Kang H Zheng, Benoit J Arsenault, Yannick Kaiser, Kay-Tee Khaw, Nicholas J Wareham, Erik SG Stroes, S Matthijs Boekholdt
Aug 21, 2019
Background Apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio and lipoprotein(a) (Lp[a]) are associated with aortic valve stenosis (AVS) disease progression. Clinical characteristics such as age, sex, and presence of...
aortic valve stenosis apoB/apoA‐I ratio lipids and lipoproteins lipoprotein(a) low‐density lipoprotein cholesterol Adult Aged aortic valve stenosis Apolipoprotein A-I Apolipoproteins B Cholesterol LDL Comorbidity Coronary Artery Disease Female Humans Incidence lipoprotein(a) Longitudinal Studies Male Middle Aged Prospective Studies United Kingdom
Emergence of a floral colour polymorphism by pollinator-mediated overdominance.
Roman T Kellenberger, Kelsey JRP Byers, Rita M De Brito Francisco, Yannick M Staedler, Amy M LaFountain, Jürg Schönenberger, Florian P Schiestl, Philipp M Schlüter
Feb 08, 2019
Maintenance of polymorphism by overdominance (heterozygote advantage) is a fundamental concept in evolutionary biology. In most examples known in nature, overdominance is a result of homozygotes suffering from deleterious...
Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes
Jakie Guertin, Yannick Kaiser, Hasanga Manikpurage, Nicolas Perrot, Raphaëlle Bourgeois, Christian Couture, Nicholas J Wareham, Yohan Bossé, Philippe Pibarot, Erik SG Stroes, Patrick Mathieu, Marie-Annick Clavel, Sébastien Thériault, S Matthijs Boekholdt, Benoit J Arsenault
Jul 26, 2021
BACKGROUND: Elevated Lp(a) (Lipoprotein(a)) levels are associated with coronary artery disease (CAD), ischemic stroke (IS), and calcific aortic valve stenosis (CAVS). Studies investigating the association between Lp(a) levels...
Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk
Benoit J Arsenault, William Pelletier, Yannick Kaiser, Nicolas Perrot, Christian Couture, Kay-Tee Khaw, Nicholas J Wareham, Yohan Bossé, Philippe Pibarot, Erik SG Stroes, Patrick Mathieu, Sébastien Thériault, S Matthijs Boekholdt
Mar 31, 2020
IMPORTANCE: Elevated lipoprotein(a) (Lp[a]) levels are associated with atherosclerotic cardiovascular diseases. The association between high Lp(a) levels and human longevity phenotypes is, however, controversial. OBJECTIVE: To...
Pooling individual participant data from randomized controlled trials
Lennard L van Wanrooij, Marieke P Hoevenaar-Blom, Nicola Coley, Tiia Ngandu, Yannick Meiller, Juliette Guillemont, Anna Rosenberg, Cathrien RL Beishuizen, Eric P Moll van Charante, Hilkka Soininen, Carol Brayne, Sandrine Andrieu, Miia Kivipelto, Edo Richard
May 22, 2020
BACKGROUND: Pooling individual participant data to enable pooled analyses is often complicated by diversity in variables across available datasets. Therefore, recoding original variables is often necessary to build a pooled...
Thresholds for Arterial Wall Inflammation Quantified by 18F-FDG PET Imaging
Fleur M van der Valk, Simone L Verweij, Koos AH Zwinderman, Aart C Strang, Yannick Kaiser, Henk A Marquering, Aart J Nederveen, Erik SG Stroes, Hein J Verberne, James HF Rudd
May 05, 2016
(18)F-FDG PET/CT Atherosclerosis Imaging Inflammation thresholds Aged Aorta Aortitis Arteritis Carotid Arteries Carotid Artery Diseases Case-Control Studies Female Fluorodeoxyglucose F18 Humans Male Middle Aged Observer Variation Plaque Atherosclerotic Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Reproducibility of Results
Pooling individual participant data from randomized controlled trials
Lennard L. van Wanrooij, Marieke P. Hoevenaar-Blom, Nicola Coley, Tiia Ngandu, Yannick Meiller, Juliette Guillemont, Anna Rosenberg, Cathrien R. L. Beishuizen, Eric P. Moll van Charante, Hilkka Soininen, Carol Brayne, Sandrine Andrieu, Miia Kivipelto, Edo Richard
May 12, 2020
Background: Pooling individual participant data to enable pooled analyses is often complicated by diversity in variables across available datasets. Therefore, recoding original variables is often necessary to build a pooled...
Proficiency Testing of Virus Diagnostics Based on Bioinformatics Analysis of Simulated In Silico High-Throughput Sequencing Data Sets.
Annika Brinkmann, Andreas Andrusch, Ariane Belka, Claudia Wylezich, Dirk Höper, Anne Pohlmann, Thomas Nordahl Petersen, Pierrick Lucas, Yannick Blanchard, Anna Papa, Angeliki Melidou, Bas B Oude Munnink, Jelle Matthijnssens, Ward Deboutte, Richard J Ellis, Florian Hansmann, Wolfgang Baumgärtner, Erhard van der Vries, Albert Osterhaus, Cesare Camma, Iolanda Mangone, Alessio Lorusso, Maurilia Marcacci, Alexandra Nunes, Miguel Pinto, Vítor Borges, Annelies Kroneman, Dennis Schmitz, Victor Max Corman, Christian Drosten, Terry C Jones, Rene S Hendriksen, Frank M Aarestrup, Marion Koopmans, Martin Beer, Andreas Nitsche
Jan 09, 2020
Quality management and independent assessment of high-throughput sequencing-based virus diagnostics have not yet been established as a mandatory approach for ensuring comparable results. The sensitivity and specificity of viral...
external quality assessment high-throughput sequencing next-generation sequencing proficiency testing virus diagnostics Computational Biology Computer Simulation Data analysis Europe Genome Viral High-Throughput Nucleotide Sequencing Humans Intersectoral Collaboration Laboratory Proficiency Testing Reproducibility of Results Sequence Analysis DNA viruses
Differential predictors for alcohol use in adolescents as a function of familial risk
Mira Tschorn, Robert C. Lorenz, Paul F. O’Reilly, Abraham Reichenberg, Erin B. Quinlan, Herta Flor, Antoine Grigis, Hugh Garavan, Bernd Ittermann, Dimitri Papadopoulos Orfanos, Luise Poustka, Sabina Millenet, Michael N. Smolka, Robert Whelan, Gunter Schumann, Michael A. Rapp, Trevor Robbins, Jeffrey Dalley, Naresh Subramaniam, David Theobald, Karl Mann, Christiane Bach, Maren Struve, Tobias Banaschewski, Marcella Rietschel, Rainer Spanagel, Frauke Nees, Mira Fauth-Bühler, Yvonne Grimmer, Mark Lathrop, Andreas Heinz, Lisa Albrecht, Nikolay Ivanov, Nicole Strache, Michael Rapp, Andreas Ströhle, Jan Reuter, Jürgen Gallinat, Henrik Walter, Isabel Gemmeke, Alexander Genauck, Caroline Parchetka, Katharina Weiß, Johann Kruschwitz, Bianca Raffaelli, Alev Isci, Laura Daedelow, Alexis Barbot, Benjamin Thyreau, Yannick Schwartz, Christophe Lalanne, Vincent Frouin, Dimitri Papadopoulos Orfanos, John Rogers, James Ireland, Dirk Lanzerath, Jianfeng Feng, Jean-Luc Martinot, Zuleima Bricaud, Fanny Gollier Briand, Hervé LemaÎtre, Ruben Miranda, Eric Artiges, Jessica Massicotte, Marie-Laure Paillère Martinot, Helene Vulser, Jani Pentillä, Irina Filippi, André Galinowski, Pauline Bezivin, Anna Cattrell, Tianye Jia, Sylvane Desrivières, Helen Werts, Lauren Topper, Laurence Reed, Chris Andrew, Catherine Mallik, Barbara Ruggeri, Charlotte Nymberg, Gareth Barker, Patricia J. Conrod, Lindsay Smith, Eva Loth, Stephanie Havatzias, Sheyda Shekarrizi, Emily Kitson, Alice Robinson, Deborah Hall, Chiara Rubino, Hannah Wright, Kerstin Stueber, Eanna Hanratty, Eleanor Kennedy, Fabiana Mesquita de Carvahlo, Argyris Stringaris, Gabriel Robert, Alex Ing, Christine Macare, Bing Xu, Tao Yu, Erin Burke Quinlan, Patrick Constant, Semiha Aydin, Ruediger Brühl, Albrecht Ihlenfeld, Bernadeta Walaszek, Michael Smolka, Thomas Hübner, Kathrin Müller, Stephan Ripke, Sarah Jurk, Eva Mennigen, Dirk Schmidt, Nora Vetter, Veronika Ziesch, Juliane H. Fröhner, Arun L. W. Bokde, Daniel Carter, Emily Walsh, Susanne O’Driscoll, Maria Leonora Fatimah Agan, Mairead McMorrow, Sinead Nugent, Colm Connolly, Eoin Dooley, Clodagh Cremen, Jennifer Jones, John O’Keefe, Martin O’Connor, Jean-Baptiste Poline, Christian Büchel, Uli Bromberg, Tahmine Fadai, Juliana Yacubian, Sophia Schneider, Maria Lobatchewa, Claire Lawrence, Craig Newman, Kay Head, Nadja Heym, Penny Gowland, Alicia Stedman, Mehri Kaviani, Susannah Taplin, Dai Stephens, Tomáš Paus, Zdenka Pausova, Amir Tahmasebi
Mar 04, 2021
Abstract: Traditional models of future alcohol use in adolescents have used variable-centered approaches, predicting alcohol use from a set of variables across entire samples or populations. Following the proposition that...
Tallo
Tommaso Jucker, Fabian Jörg Fischer, Jérôme Chave, David A Coomes, John Caspersen, Arshad Ali, Grace Jopaul Loubota Panzou, Ted R Feldpausch, Daniel Falster, Vladimir A Usoltsev, Stephen Adu-Bredu, Luciana F Alves, Mohammad Aminpour, Ilondea B Angoboy, Niels PR Anten, Cécile Antin, Yousef Askari, Rodrigo Muñoz, Narayanan Ayyappan, Patricia Balvanera, Lindsay Banin, Nicolas Barbier, John J Battles, Hans Beeckman, Yannick E Bocko, Ben Bond-Lamberty, Frans Bongers, Samuel Bowers, Thomas Brade, Michiel van Breugel, Arthur Chantrain, Rajeev Chaudhary, Jingyu Dai, Michele Dalponte, Kangbéni Dimobe, Jean-Christophe Domec, Jean-Louis Doucet, Remko A Duursma, Moisés Enríquez, Karin Y van Ewijk, William Farfán-Rios, Adeline Fayolle, Eric Forni, David I Forrester, Hammad Gilani, John L Godlee, Sylvie Gourlet-Fleury, Matthias Haeni, Jefferson S Hall, Jie-Kun He, Andreas Hemp, José L Hernández-Stefanoni, Steven I Higgins, Robert J Holdaway, Kiramat Hussain, Lindsay B Hutley, Tomoaki Ichie, Yoshiko Iida, Hai-Sheng Jiang, Puspa Raj Joshi, Hasan Kaboli, Maryam Kazempour Larsary, Tanaka Kenzo, Brian D Kloeppel, Takashi Kohyama, Suwash Kunwar, Shem Kuyah, Jakub Kvasnica, Siliang Lin, Emily R Lines, Hongyan Liu, Craig Lorimer, Jean-Joël Loumeto, Yadvinder Malhi, Peter L Marshall, Eskil Mattsson, Radim Matula, Jorge A Meave, Sylvanus Mensah, Xiangcheng Mi, Stéphane Momo, Glenn R Moncrieff, Francisco Mora, Sarath P Nissanka, Kevin L O'Hara, Steven Pearce, Raphaël Pelissier, Pablo L Peri, Pierre Ploton, Lourens Poorter, Mohsen Javanmiri Pour, Hassan Pourbabaei, Juan Manuel Dupuy-Rada, Sabina C Ribeiro, Casey Ryan, Anvar Sanaei, Jennifer Sanger, Michael Schlund, Giacomo Sellan, Alexander Shenkin, Bonaventure Sonké, Frank J Sterck, Martin Svátek, Kentaro Takagi, Anna T Trugman, Farman Ullah, Matthew A Vadeboncoeur, Ahmad Valipour, Mark C Vanderwel, Alejandra G Vovides, Weiwei Wang, Li-Qiu Wang, Christian Wirth, Murray Woods, Wenhua Xiang, Fabiano de Aquino Ximenes, Yaozhan Xu, Toshihiro Yamada, Miguel A Zavala
Jun 29, 2022
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