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Results: 312
YAP is essential for tissue tension to ensure vertebrate 3D body shape
Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S. F Gabriel Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl Philipp Heisenberg, Makoto Furutani-Seiki
May 14, 2015
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup which must in turn be correctly...
A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.
Gernot Walko, Samuel Woodhouse, Angela Oliveira Pisco, Emanuel Rognoni, Kifayathullah Liakath-Ali, Beate M Lichtenberger, Ajay Mishra, Stephanie B Telerman, Priyalakshmi Viswanathan, Meike Logtenberg, Lisa M Renz, Giacomo Donati, Sven R Quist, Fiona M Watt
Feb 07, 2019
Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal...
YAP is essential for tissue tension to ensure vertebrate 3D body shape
Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S. F Gabriel Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl Philipp Heisenberg, Makoto Furutani-Seiki
May 14, 2015
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup which must in turn be correctly...
Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an essential aspect of neurogenesis. The Hippo signaling pathway has recently been identified as...
The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an essential aspect of neurogenesis. The Hippo signaling pathway has recently been identified as...
The Grizzly, November 14, 2024
Kate Horan, Connor McCarney, Sidney Belleroche, Caitlin Cunnane, Sophia Kumar, Stella Bower, Emily Veasey, Mary Lauren Franz, Kylie Ruggiero
Jan 01, 0001
"Keep Moving Forward" Hora De Café Bears on Trial A Dorm Cat's Story The Yap: A Recession of "Meet-Cute" Stories? Bears' Zelinske Defies the Odds Gymnastics Coach DeLorme Does It All
Ursinus College Collegeville Pennsylvania newspaper Dylan McHugh Football Xochitl Shuru pre-law studies Ella Schneider dating Alex Zelinske Swimming Alyssa DeLorme gymnastics cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, October 31, 2024
Beetlejuice Breakout: Grizzly Edition Spooky Scary STDs UC Theater Presents an Agatha Christie Double Bill! The Monsters are Due on Main Street Creating "Bullshit" Opinions: The Yap With Emily Veasey Nerf Club: A Merry...
Ursinus College Collegeville Pennsylvania newspaper escape rooms peer advocates Safe Sex Theater department Naila Twyman horror fiction Halloween costumes nerf club lacrosse team Trinity Reformed Church cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The road to recovery
Lindsay F Banin, Elizabeth H Raine, Lucy M Rowland, Robin L Chazdon, Stuart W Smith, Nur Estya Binte Rahman, Adam Butler, Christopher Philipson, Grahame G Applegate, E Petter Axelsson, Sugeng Budiharta, Siew Chin Chua, Mark EJ Cutler, Stephen Elliott, Elva Gemita, Elia Godoong, Laura LB Graham, Robin M Hayward, Andy Hector, Ulrik Ilstedt, Joel Jensen, Srinivasan Kasinathan, Christopher J Kettle, Daniel Lussetti, Benjapan Manohan, Colin Maycock, Kang Min Ngo, Michael J O'Brien, Anand M Osuri, Glen Reynolds, Yap Sauwai, Stefan Scheu, Mangarah Silalahi, Eleanor M Slade, Tom Swinfield, David A Wardle, Charlotte Wheeler, Kok Loong Yeong, David FRP Burslem
Dec 15, 2022
Current policy is driving renewed impetus to restore forests to return ecological function, protect species, sequester carbon and secure livelihoods. Here we assess the contribution of tree planting to ecosystem restoration in...
The Grizzly, December 5, 2024
Kate Horan, Zach Cosme, Ashley Adam, Renee Washart, Emily Veasey, Sidney Belleroche, Hadley Whitman, Adam Denn
Jan 01, 0001
The Case of the Missing Lower Wismer Doors Seen the Zine? SAAC's Annual Holiday Food Drive Representation Exploration: Capstone Excerpt Campus Squirrels Pack Up for the Holidays The Yap With Emily Veasey...
Ursinus College Collegeville Pennsylvania newspaper Wismer dining hall zines Student Athlete Advisory Committee Diversity squirrels Social Media Wellness field hockey Basketball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The road to recovery
Lindsay F Banin, Elizabeth H Raine, Lucy M Rowland, Robin L Chazdon, Stuart W Smith, Nur Estya Binte Rahman, Adam Butler, Christopher Philipson, Grahame G Applegate, E Petter Axelsson, Sugeng Budiharta, Siew Chin Chua, Mark EJ Cutler, Stephen Elliott, Elva Gemita, Elia Godoong, Laura LB Graham, Robin M Hayward, Andy Hector, Ulrik Ilstedt, Joel Jensen, Srinivasan Kasinathan, Christopher J Kettle, Daniel Lussetti, Benjapan Manohan, Colin Maycock, Kang Min Ngo, Michael J O'Brien, Anand M Osuri, Glen Reynolds, Yap Sauwai, Stefan Scheu, Mangarah Silalahi, Eleanor M Slade, Tom Swinfield, David A Wardle, Charlotte Wheeler, Kok Loong Yeong, David FRP Burslem
Nov 15, 2022
Comprehensive review on some food-derived bioactive peptides with anti-hypertension therapeutic potential for angiotensin-converting enzyme (ACE) inhibition
Angiotensin-converting enzyme (ACE) inhibitory peptides have lately attracted interest since functional foods that help maintain homeostatic regulations have been developed. Rarely discussed are the intrinsic ACE-peptide...
Comprehensive review on some food-derived bioactive peptides with anti-hypertension therapeutic potential for angiotensin-converting enzyme (ACE) inhibition
Angiotensin-converting enzyme (ACE) inhibitory peptides have lately attracted interest since functional foods that help maintain homeostatic regulations have been developed. Rarely discussed are the intrinsic ACE-peptide...
A Novel Inducible Prophage from Burkholderia Vietnamiensis G4 is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia.
Rebecca Weiser, Zhong Ling Yap, Ashley Otter, Brian V Jones, Jonathan Salvage, Julian Parkhill, Eshwar Mahenthiralingam
Jun 18, 2020
Burkholderia species have environmental, industrial and medical significance, and are important opportunistic pathogens in individuals with cystic fibrosis (CF). Using a combination of existing and newly determined genome...
The Hippo pathwaya
The Hippo pathway is a conserved pathway that interconnects with several other pathways to regulate organ growth, tissue homeostasis and regeneration, and stem cell self-renewal. This pathway is unique in its capacity to...
The Hippo pathwaya
The Hippo pathway is a conserved pathway that interconnects with several other pathways to regulate organ growth, tissue homeostasis and regeneration, and stem cell self-renewal. This pathway is unique in its capacity to...
A Novel Inducible Prophage from Burkholderia Vietnamiensis G4 is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia
Burkholderia species have environmental, industrial and medical significance, and are important opportunistic pathogens in individuals with cystic fibrosis (CF). Using a combination of existing and newly determined genome...
Use of Digital Finance Platforms for Personal Finance Management in Rural China
This study examined the antecedents and consequences of the use of digital finance platforms to manage personal finance of rural people in China. The conceptual framework of the study was developed from the integration of...
Published by: IGI Global Scientific Publishing
Asymmetric division of contractile domains couples cell positioning and fate specification.
Jean-Léon Maître, Hervé Turlier, Rukshala Illukkumbura, Björn Eismann, Ritsuya Niwayama, François Nédélec, Takashi Hiiragi
Aug 06, 2020
During pre-implantation development, the mammalian embryo self-organizes into the blastocyst, which consists of an epithelial layer encapsulating the inner-cell mass (ICM) giving rise to all embryonic tissues. In mice, oriented...
Adaptor Proteins Signal Transducing Animals Blastocyst Blastocyst Inner Cell Mass Blastomeres Cell Cycle Proteins Cell Differentiation Cell Division Cell Lineage Cell Movement Cell Polarity Embryo Mammalian Embryonic Development Female Male Mice Phosphoproteins Protein Transport Reproducibility of Results YAP-Signaling Proteins
ROBO3s
Marcel Werner, Anna Dyas, Iwan Parfentev, Geske E Schmidt, Iga K Mieczkowska, Lukas C Müller-Kirschbaum, Claudia Müller, Stefan Kalkhof, Oliver Reinhardt, Henning Urlaub, Frauke Alves, Julia Gallwas, Evangelos Prokakis, Florian Wegwitz
Sep 03, 2022
Basal-like breast cancer (BLBC) is a highly aggressive breast cancer subtype frequently associated with poor prognosis. Due to the scarcity of targeted treatment options, conventional cytotoxic chemotherapies frequently remain...
Developing a lifestyle intervention program for overweight or obese preconception, pregnant and postpartum women using qualitative methods.
Chee Wai Ku, Shu Hui Leow, Lay See Ong, Christina Erwin, Isabella Ong, Xiang Wen Ng, Jacinth JX Tan, Fabian Yap, Jerry Kok Yen Chan, See Ling Loy
Feb 15, 2022
The time period before, during and after pregnancy represents a unique opportunity for interventions to cultivate sustained healthy lifestyle behaviors to improve the metabolic health of mothers and their offspring. However, the...
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