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We Decided we Would Commit Suicide but we Couldn’t
A thematic analysis of the extreme level of depression circulating on the lockdown society during the Covid-19 situation reveals problems and challenges that the young generation faced. They expressed the hardships of surviving...
miR-155 induction is a marker of murine norovirus infection but does not contribute to control of replication in vivo.
Background: Due to their role in fine-tuning cellular protein expression, microRNAs both promote viral replication and contribute to antiviral responses, for a range of viruses. The interactions between norovirus and the...
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The organizational stressors encountered by athletes with a disability
Organisational stressors have been found to be prevalent and problematic for sport performers, with research identifying demographic differences in the stressors encountered. Nevertheless, extant sport psychology research on the...
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The organizational stressors encountered by athletes with a disability
Organisational stressors have been found to be prevalent and problematic for sport performers, with research identifying demographic differences in the stressors encountered. Nevertheless, extant sport psychology research on the...
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Different Effects of Vascular Aging on Ischemic Predisposition in Healthy Men and Women.
Invasive studies of the twentieth century showed the value of aortic pressure-time integrals as markers of myocardial oxygen demand and supply. More recent studies have used these concepts to evaluate the mechanisms of ischemic...
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The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness.
Stiffening of the aorta is an important independent risk factor for myocardial infarction and stroke. Yet its genetics is complex and little is known about its molecular drivers. We have identified for the first time, tagSNPs in...
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Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.
Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a significant cause of morbidity and mortality in all age groups. The recent finding that HuNoV can be propagated in B cells and mucosa-derived...
Published by: mBio
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells.
Background: Norovirus, also known as the winter vomiting bug, is the predominant cause of non-bacterial gastroenteritis worldwide. Disease control is predicated on a robust innate immune response during the early stages of...
Published by: Wellcome Open Res

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