Search
Results: 1289
Structural and functional correlates of the response to deep brain stimulation at ventral capsule/ventral striatum region for treatment-resistant depression.
Yijie Lai, Lulin Dai, Tao Wang, Yingying Zhang, Yijie Zhao, Fengting Wang, Qimin Liu, Shikun Zhan, Dianyou Li, Haiyan Jin, Yiru Fang, Valerie Voon, Bomin Sun
Jan 05, 2023
Acute Time-Locked Alpha Frequency Subthalamic Stimulation Reduces Negative Emotional Bias in Parkinson's Disease.
Alekhya Mandali, Luis Manssuer, Yijie Zhao, Chencheng Zhang, Linbin Wang, Qiong Ding, Yixin Pan, Dianyou Li, Bomin Sun, Valerie Voon
Dec 17, 2020
BACKGROUND: Emotional processing is a core cognitive process cutting across neuropsychiatric disorders. Understanding the neurophysiological features underlying depressive symptoms and their sensitivity to modulation is critical...
Analyzing E-Commerce Market Data Using Deep Learning Techniques to Predict Industry Trends
Faced with challenges in sales predicting research, this article combines the capabilities of deep learning algorithms in handling complex tasks and unstructured data. Through analyzing consumer behavior, it selects factors...
Published by: IGI Global Scientific Publishing
Water management and agricultural intensification of rice farming at the late-Neolithic site of Maoshan, Lower Yangtze River, China
Intensifying water management for rice farming and related land use involves increasing labour investment in transforming local landscapes. By applying geoarchaeological investigation at the well-preserved...
Xenopus DPPA2 is a Direct Inhibitor of Microtubule Polymerization Required for Nuclear Assembly
John Zhao Xue
Jan 01, 0001
The eukaryotic nucleus mediates the genomic functions of information storage and gene expression, but must be completely rebuilt after every open mitosis as well as during fertilization. Nuclear abnormalities are observed in...
Published by: Rockefeller University
Variable Selection for a Categorical Varying-Coefficient Model with Identifications for Determinants of Body Mass Index
Obesity has become one of the major public health issues during the last three decades. A considerable number of determinants have been proposed for body mass index (BMI) by a large range of studies from multiple disciplines. In...
Variable Selection for a Categorical Varying-Coefficient Model with Identifications for Determinants of Body Mass Index
Obesity has become one of the major public health issues during the last three decades. A considerable number of determinants have been proposed for body mass index (BMI) by a large range of studies from multiple disciplines. In...
Human and mouse leukocytes
Simón Méndez-Ferrer
Mar 19, 2018
In this issue of Blood, Zhao et al use a humanized mouse model to investigate the mechanisms driving daily oscillations in circulating human and murine leukocytes.1 In the same mice, they find human and murine circulating...
Effects of Bilateral Subthalamic Nucleus Stimulation on Depressive Symptoms and Cerebral Glucose Metabolism in Parkinson's Disease
Xiaoxiao Zhang, Huiwei Zhang, Zhengyu Lin, Daniel AN Barbosa, Yijie Lai, Casey H Halpern, Valerie Voon, Dianyou Li, Chencheng Zhang, Bomin Sun
Jun 15, 2022
Subthalamic nucleus (STN) deep brain stimulation (DBS) can improve motor symptoms in Parkinson's disease (PD), as well as potentially improving otherwise intractable comorbid depressive symptoms. To address the latter issue, we...
Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition.
Diana Zabini, Elise Granton, Yijie Hu, Maria Zena Miranda, Ulrike Weichelt, Sandra Breuils Bonnet, Sébastien Bonnet, Nicholas W Morrell, Kim A Connelly, Steeve Provencher, Bahil Ghanim, Walter Klepetko, Andrea Olschewski, Andras Kapus, Wolfgang M Kuebler
Jan 04, 2019
RATIONALE: Vascular remodeling in pulmonary arterial hypertension (PAH) results from smooth muscle cell hypertrophy and proliferation of vascular cells. Loss of BMPR-II (bone morphogenetic protein receptor 2) signaling and...
SMAD3 myocardin-related transcription factor pulmonary arterial hypertension Vascular Remodeling Animals Cell Movement Cell Proliferation Disease Models Animal Down-Regulation Humans Hypertension Pulmonary Male Muscle Cells Random Allocation Rats Rats Sprague-Dawley Sensitivity and Specificity Smad3 Protein Transcription Factors Transfection Transforming Growth Factor beta Vascular Remodeling
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose
Lin-E Guo, Yuan Hong, Shu-Ying Zhang, Miao Zhang, Xiao-Sheng Yan, Jin-Lian Cao, Zhao Li, Tony D James, Yun-Bao Jiang
Dec 21, 2018
Chiral recognition remains a major challenge in the area of molecular receptor design. With this research, we set out to explore the use of proline-based receptors for chiral recognition. Importantly, the proline structure...
Impact of Correlated Noise on the Mass Precision of Earth-analog Planets in Radial Velocity Surveys
Jacob K. Luhn, Eric B. Ford, Zhao Guo, Christian Gilbertson, Patrick Newman, Peter Plavchan, Jennifer A. Burt, Johanna Teske, Arvind F. Gupta
Feb 10, 2023
Characterizing the masses and orbits of near-Earth-mass planets is crucial for interpreting observations from future direct imaging missions (e.g., HabEx, LUVOIR). Therefore, the Exoplanet Science Strategy report recommended...
Published by: The American Astronomical Society
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
In situ structure of the AcrAB-TolC efflux pump at subnanometer resolution.
Muyuan Chen, Xiaodong Shi, Zhili Yu, Guizhen Fan, Irina I Serysheva, Matthew L Baker, Ben F Luisi, Steven J Ludtke, Zhao Wang
Sep 16, 2021
The tripartite AcrAB-TolC assembly, which spans both the inner and outer membranes in Gram-negative bacteria, is an efflux pump that contributes to multidrug resistance. Here, we present the in situ structure of full-length...
AcrAB-TolC cryo-ET in situ multidrug efflux pump subnanometer resolution Allosteric Regulation Bacterial Outer Membrane Proteins Carrier Proteins Cryoelectron Microscopy Electron Microscope Tomography Escherichia coli Escherichia coli Proteins Ligands Lipoproteins Membrane Transport Proteins Models Molecular Multidrug Resistance-Associated Proteins Protein Conformation
Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose
Lin-E Guo, Yuan Hong, Shu-Ying Zhang, Miao Zhang, Xiao-Sheng Yan, Jin-Lian Cao, Zhao Li, Tony D James, Yun-Bao Jiang
Dec 21, 2018
Chiral recognition remains a major challenge in the area of molecular receptor design. With this research, we set out to explore the use of proline-based receptors for chiral recognition. Importantly, the proline structure...
|
|< |
< |
1 |