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Stem Cell Therapy and Biomedical Applications
Stem cells have revolutionized research and applications for biomedical sciences. In combination with gene therapy as well as regenerative medicine, stem cells have led to several breakthrough technologies. Utilizing these...
Published by: Harrisburg University of Science and Technology
Adrenoleukodystrophy (ALD)
First reported case in 1910, ALD results in serious cognitive and developmental issues. Adult form reported in 1976. Gene of cause identified in 1993 by Mosser et al. X-linked, mutation on ABCD1 gene codes for VLCFA ...
Published by: Harrisburg University of Science and Technology
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.
Matthew A White, Eosu Kim, Amanda Duffy, Robert Adalbert, Benjamin U Phillips, Owen M Peters, Jodie Stephenson, Sujeong Yang, Francesca Massenzio, Ziqiang Lin, Simon Andrews, Anne Segonds-Pichon, Jake Metterville, Lisa M Saksida, Richard Mead, Richard R Ribchester, Youssef Barhomi, Thomas Serre, Michael P Coleman, Justin R Fallon, Timothy J Bussey, Robert H Brown, Jemeen Sreedharan
Jun 13, 2018
Amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) constitutes a devastating disease spectrum characterized by 43-kDa TAR DNA-binding protein (TDP-43) pathology. Understanding how TDP-43 contributes to...
Amyotrophic Lateral Sclerosis Animals Brain Choice Behavior Cognition Disorders Conditioning Operant DNA-Binding Proteins Dementia Disease Models Animal Female Gene Expression Regulation Male Memory Disorders Mice Mice Inbred C57BL Mice Transgenic Motor Activity Mutation Neuromuscular Junction Psychomotor Performance Reaction Time
dialogi
Nicholas M Katritsis, Anika Liu, Gehad Youssef, Sanjay Rathee, Méabh MacMahon, Woochang Hwang, Lilly Wollman, Namshik Han
Aug 23, 2022
Drug-Induced Liver Injury (DILI), despite its low occurrence rate, can cause severe side effects or even lead to death. Thus, it is one of the leading causes for terminating the development of new, and restricting the use of...
DILI C
Sanjay Rathee, Meabh MacMahon, Anika Liu, Nicholas M Katritsis, Gehad Youssef, Woochang Hwang, Lilly Wollman, Namshik Han
Jul 14, 2022
Drug-induced liver injury (DILI) is a class of adverse drug reactions (ADR) that causes problems in both clinical and research settings. It is the most frequent cause of acute liver failure in the majority of Western countries...
Defining the clonal dynamics leading to mouse skin tumour initiation.
Adriana Sánchez-Danés, Edouard Hannezo, Jean-Christophe Larsimont, Mélanie Liagre, Khalil Kass Youssef, Benjamin D Simons, Cédric Blanpain
Aug 16, 2016
Heritability of overlapping impulsivity and compulsivity dimensional phenotypes.
Jeggan Tiego, Samuel R Chamberlain, Ben J Harrison, Andrew Dawson, Lucy Albertella, George J Youssef, Leonardo F Fontenelle, Murat Yücel
Nov 02, 2020
Impulsivity and compulsivity are traits relevant to a range of mental health problems and have traditionally been conceptualised as distinct constructs. Here, we reconceptualised impulsivity and compulsivity as partially...
Collaborative Bullwhip Effect-Oriented Bi-Objective Optimization for Inference-Based Weighted Moving Average Forecasting in Decentralized Supply Chain
Downstream demand inference (DDI) emerged in the supply chain theory, allowing an upstream actor to infer the demand occurring at his formal downstream actor without need of information sharing. Literature showed that...
Published by: IGI Global Scientific Publishing
Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening.
Abiola Senok, Hanan Alsuwaidi, Yusrah Atrah, Ola Al Ayedi, Janan Al Zahid, Aaron Han, Asma Al Marzooqi, Saba Al Heialy, Basel Altrabulsi, Laila AbdelWareth, Youssef Idaghdour, Raghib Ali, Tom Loney, Alawi Alsheikh-Ali
Nov 20, 2020
PURPOSE: With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive, self-collected specimen like saliva will be...
Chaperone-like protein DAY plays critical roles in photomorphogenesis.
Ho-Seok Lee, Ilyeong Choi, Young Jeon, Hee-Kyung Ahn, Huikyong Cho, JiWoo Kim, Jae-Hee Kim, Jung-Min Lee, SungHee Lee, Julian Bünting, Dong Hye Seo, Tak Lee, Du-Hwa Lee, Insuk Lee, Man-Ho Oh, Tae-Wuk Kim, Youssef Belkhadir, Hyun-Sook Pai
Sep 05, 2021
Photomorphogenesis, light-mediated development, is an essential feature of all terrestrial plants. While chloroplast development and brassinosteroid (BR) signaling are known players in photomorphogenesis, proteins that regulate...
Arabidopsis Arabidopsis Proteins Brassinosteroids Chlorophyll Chloroplasts Etiolation Gene Expression Regulation Plant Gene Knockdown Techniques HSP40 Heat-Shock Proteins LIGHT Membrane Proteins Microtubule-Associated Proteins Morphogenesis Mutation Plants Genetically Modified Protein Kinases RNA-seq Recombinant Proteins Seedlings Signal Transduction
Chaperone-like protein DAY plays critical roles in photomorphogenesis.
Ho-Seok Lee, Ilyeong Choi, Young Jeon, Hee-Kyung Ahn, Huikyong Cho, JiWoo Kim, Jae-Hee Kim, Jung-Min Lee, SungHee Lee, Julian Bünting, Dong Hye Seo, Tak Lee, Du-Hwa Lee, Insuk Lee, Man-Ho Oh, Tae-Wuk Kim, Youssef Belkhadir, Hyun-Sook Pai
Aug 11, 2021
Photomorphogenesis, light-mediated development, is an essential feature of all terrestrial plants. While chloroplast development and brassinosteroid (BR) signaling are known players in photomorphogenesis, proteins that regulate...
Chloroplasts Plants Genetically Modified Arabidopsis Chlorophyll Protein Kinases Microtubule-Associated Proteins Membrane Proteins Arabidopsis Proteins Recombinant Proteins Signal Transduction Gene Expression Regulation Plant Morphogenesis Mutation LIGHT HSP40 Heat-Shock Proteins Gene Knockdown Techniques Brassinosteroids Etiolation Seedlings RNA-seq
Published by: Nature Communications
Chaperone-like protein DAY plays critical roles in photomorphogenesis
Ho-Seok Lee, Ilyeong Choi, Young Jeon, Hee-Kyung Ahn, Huikyong Cho, JiWoo Kim, Jae-Hee Kim, Jung-Min Lee, SungHee Lee, Julian Bünting, Dong Hye Seo, Tak Lee, Du-Hwa Lee, Insuk Lee, Man-Ho Oh, Tae-Wuk Kim, Youssef Belkhadir, Hyun-Sook Pai
Jul 07, 2021
Abstract: Photomorphogenesis, light-mediated development, is an essential feature of all terrestrial plants. While chloroplast development and brassinosteroid (BR) signaling are known players in photomorphogenesis, proteins that...
Maternal Early-Life Risk Factors and Later Gestational Diabetes Mellitus
Nirmin F Juber, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatima Mezhal, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag Ali, Naima Oumeziane, Omar El-Shahawy, Scott Sherman, Sharifa AlBlooshi, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Raghib Ali
Sep 25, 2022
Limited studies have focused on maternal early-life risk factors and the later development of gestational diabetes mellitus (GDM). We aimed to estimate the GDM prevalence and examine the associations of maternal early-life risk...
GDM UAE UAE healthy future study UAEHFS United Arab Emirates EPIDEMIOLOGY Gestational diabetes mellitus maternal early-life factor Pregnancy Birth Weight Blood Glucose Blood Glucose Self-Monitoring Child Cross-Sectional Studies Diabetes Gestational Female Humans Infant Newborn Pregnancy Retrospective Studies Risk Factors
Book Review: Youssef Cassis, Richard S. Grossman & Catherine R. Schenk eds., The Oxford handbook of banking and financial history (Oxford
SA-MI Schneider
Jan 25, 2017
The Oxford Handbook of Banking and Financial History is a timely work of synthesis that consolidates the recent resurgence of scholarly interest in the long-term evolution of the global financial system. Its editors have...
Maternal Early-Life Risk Factors and Later Gestational Diabetes Mellitus
Nirmin F Juber, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatima Mezhal, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag Ali, Naima Oumeziane, Omar El-Shahawy, Scott Sherman, Sharifa AlBlooshi, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Raghib Ali
Aug 20, 2022
Limited studies have focused on maternal early-life risk factors and the later development of gestational diabetes mellitus (GDM). We aimed to estimate the GDM prevalence and examine the associations of maternal early-life risk...
Metabolic Syndrome in Fasting and Non-Fasting Participants
Fatima Mezhal, Amar Ahmad, Abdishakur Abdulle, Andrea Leinberger-Jabari, Abderrahim Oulhaj, Abdulla AlJunaibi, Abdulla Alnaeemi, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Manal Alblooshi, Mohammad Al-Houqani, Mohammad Hag Ali, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Nov 04, 2022
High prevalence of cardiometabolic risk factors amongst young adults in the United Arab Emirates
Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Apr 15, 2023
Background
Cardiovascular disease (CVD) is the leading cause of death in the world. In the United Arab Emirates (UAE), it accounts for 40% of mortality. CVD is caused by multiple cardiometabolic risk factors (CRFs)...
Hypertension obesity cardiovascular disease Dyslipidemia Central obesity Non-communicable disease cardiometabolic risk factors Dysglycemia Humans Cardiovascular Diseases prevalence Risk Factors Adult United Arab Emirates Female Male Dyslipidemias Young Adult obesity Abdominal
Published by: BMC cardiovascular disorders
High prevalence of cardiometabolic risk factors amongst young adults in the United Arab Emirates
Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Mar 15, 2023
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in the world. In the United Arab Emirates (UAE), it accounts for 40% of mortality. CVD is caused by multiple cardiometabolic risk factors (CRFs) including...
cardiometabolic risk factors cardiovascular disease Central obesity Dysglycemia Dyslipidemia Hypertension Non-communicable disease obesity Male Humans Female Young Adult Adult United Arab Emirates obesity Abdominal cardiometabolic risk factors prevalence obesity Cardiovascular Diseases Hypertension Dyslipidemias Risk Factors
Association Between Self-Reported Polycystic Ovary Syndrome with Chronic Diseases Among Emiratis
Nirmin F Juber, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag-Ali, Naima Oumeziane, Scott Sherman, Syed M Shah, Wael Almahmeed, Youssef Idaghdour, Tom Loney, Omar El-Shahawy, Raghib Ali
Mar 26, 2023
Purpose
This study aimed to assess the prevalence of self-reported polycystic ovary syndrome (PCOS) among Emiratis and examine bi-directional associations of PCOS with self-reported chronic diseases, namely: diabetes...
EPIDEMIOLOGY POLYCYSTIC OVARY SYNDROME United Arab Emirates women’s health Self-reported Diagnosis UAE healthy future study
Published by: International journal of women's health
Physiological effects and subjective tolerability of prone positioning in COVID-19 and healthy hypoxic challenge.
Akhilesh Jha, Fangyue Chen, Sam Mann, Ravi Shah, Randa Abu-Youssef, Holly Pavey, Helen Lin-Jia-Qi, Josh Cara, Daniel Cunningham, Kate Fitzpatrick, Celine Goh, Renee Ma, Souradip Mookerjee, Vaitehi Nageshwaran, Timothy Old, Catherine Oxley, Louise Jordon, Mayurun Selvan, Anna Wood, Andrew Ying, Chen Zhang, Dariusz Wozniak, Iain Goodhart, Frances Early, Marie Fisk, Jonathan Fuld
Mar 13, 2022
BACKGROUND: Prone positioning has a beneficial role in coronavirus disease 2019 (COVID-19) patients receiving ventilation but lacks evidence in awake non-ventilated patients, with most studies being retrospective, lacking...
Metabolic Syndrome in Fasting and Non-Fasting Participants
Fatima Mezhal, Amar Ahmad, Abdishakur Abdulle, Andrea Leinberger-Jabari, Abderrahim Oulhaj, Abdulla AlJunaibi, Abdulla Alnaeemi, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Manal Alblooshi, Mohammad Al-Houqani, Mohammad Hag Ali, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Nov 15, 2022
Metabolic Syndrome in Fasting and Non-Fasting Participants
Fatima Mezhal, Amar Ahmad, Abdishakur Abdulle, Andrea Leinberger-Jabari, Abderrahim Oulhaj, Abdulla AlJunaibi, Abdulla Alnaeemi, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Manal Alblooshi, Mohammad Al-Houqani, Mohammad Hag Ali, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Dec 12, 2022
INTRODUCTION: Metabolic syndrome (MetS) is a multiplex of risk factors that predispose people to the development of diabetes and cardiovascular disease (CVD), two of the major non-communicable diseases that contribute to...
The interrelationship and accumulation of cardiometabolic risk factors amongst young adults in the United Arab Emirates
Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, E Murat Tuzcu, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Micheal Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Scherman, Syed M Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Dec 15, 2021
INTRODUCTION: Similar to other non-communicable diseases (NCDs), people who develop cardiovascular disease (CVD) typically have more than one risk factor. The clustering of cardiovascular risk factors begins in youth, early...
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