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Results: 33
The role of acetic acid in orthopaedic surgery.
Yousuf Hashmi, Andrew Kailin Zhou, Anam Jawaid, Anli Yue Zhou, Vianca Shah, Azeem Thahir, Matija Krkovic
May 30, 2022
Acetic acid has become more commonly used in orthopaedic surgery. The purposed roles include biofilm eradication and surgical debridement, postoperative scar reduction and managing soft tissue injuries. Current research is...
Determinants of transgender job satisfaction
The purpose of this study is to establish as well as examine the validity and reliability of the instrument to measure the perception of working transgender job satisfaction. The instrument was adopted and adapted from the...
Published by: Department of History, University of Karachi
On Modelling Process Aspects With Deontic Event-Calculus
Mustafa Hashmi
Jan 01, 2022
Intuitive and faithful modelling the compliance requirements about the process aspects is a prerequisite for their automated compliance checking. Several formalisms with varying degrees of expressiveness for modelling compliance...
Published by: IGI Global Scientific Publishing
Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases.
B-cell targeted therapies (BCTT) are now widely used in autoimmune rheumatic diseases, including SLE, antineutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis. Early studies suggested that rituximab did...
Automated Glucose Control
Automated blood glucose control for diabetes mellitus is a highly desired pursuit of researchers around the globe. Advancement in sensing and control capabilities has paced the development of closed-loop control systems for...
Published by: IGI Global Scientific Publishing
Electrochemical activation of cp∗ iridium complexes for electrode-driven water-oxidation catalysis
J.M. Thomsen, S.W. Sheehan, S.M. Hashmi, J. Campos, U. Hintermair, R.H. Crabtree, G.W. Brudvig
Oct 01, 2014
Organometallic iridium complexes bearing oxidatively stable chelate ligands are precursors for efficient homogeneous water-oxidation catalysts (WOCs), but their activity in oxygen evolution has so far been studied almost...
Availability of Community-Based Mentoring Program for Children and Youth
Abstract
This study aimed to explore the availability of community-based mentoring programs for children and youth within the various communities including Bohri, Ismaili, Memon, Parsi, Christian, and Hindu in Karachi...
children development community-based programs Karachi-based communities mentoring programs youth development Education
Published by: Department of History, University of Karachi
Epidemiology, clinical features, and impact of food habits on the risk of hepatocellular carcinoma
M Al-Amin Shawon, M Abul Khair Yousuf, Enayetur Raheem, Sium Ahmed, Tyeaba Tasnim Dipti, Mohammad Razuanul Hoque, Hiroaki Taniguchi, M Rezaul Karim
Apr 30, 2020
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer mortality worldwide. Infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is the most predominant cause of...
Hyperventilation Syndrome
Christopher YK Williams, Robert WK Williams, Richard Knight, Syed Hashmi, Neil Donnelly, Manohar Bance
Apr 17, 2020
OBJECTIVE: To explore the Nijmegen Questionnaire (NQ) and its relationship to vestibular function tests and symptoms in patients with dizziness; to compare patient characteristics between those with a positive Nijmegen score and...
Electrochemical activation of cp∗ iridium complexes for electrode-driven water-oxidation catalysis
J.M. Thomsen, S.W. Sheehan, S.M. Hashmi, J. Campos, U. Hintermair, R.H. Crabtree, G.W. Brudvig
Oct 01, 2014
Organometallic iridium complexes bearing oxidatively stable chelate ligands are precursors for efficient homogeneous water-oxidation catalysts (WOCs), but their activity in oxygen evolution has so far been studied almost...
Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids.
Ali Hashmi, Sham Tlili, Pierre Perrin, Molly Lowndes, Hanna Peradziryi, Joshua M Brickman, Alfonso Martínez Arias, Pierre-François Lenne
May 11, 2022
Shaping the animal body plan is a complex process that involves the spatial organization and patterning of the different germ layers. Recent advances in live imaging have started to unravel the cellular choreography underlying...
Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon
Yousuf A. Khan, Irwin Jungreis, James C. Wright, Jonathan M. Mudge, Jyoti S. Choudhary, Andrew E. Firth, Manolis Kellis
Mar 06, 2021
Abstract: Background: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in...
Probing the viability of oxo-coupling pathways in iridium-catalyzed oxygen evolution
Jonathan Graeupner, Ulrich Hintermair, Daria L. Huang, Julianne M. Thomsen, Mike Takase, Jesus Campos, Sara M. Hashmi, Menachem Elimelech, Gary W. Brudvig, Robert H. Crabtree
Oct 14, 2013
A series of Cp*IrIII dimers has been synthesized to elucidate the mechanistic viability of radical oxo-coupling pathways in iridium-catalyzed O2 evolution. The oxidative stability of the precursors towards...
Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids.
Ali Hashmi, Sham Tlili, Pierre Perrin, Molly Lowndes, Hanna Peradziryi, Joshua M Brickman, Alfonso Martínez Arias, Pierre-François Lenne
Apr 22, 2022
Shaping the animal body plan is a complex process that involves the spatial organization and patterning of the different germ layers. Recent advances in live imaging have started to unravel the cellular choreography underlying...
Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon
Yousuf A. Khan, Irwin Jungreis, James C. Wright, Jonathan M. Mudge, Jyoti S. Choudhary, Andrew E. Firth, Manolis Kellis
Jun 06, 2020
Abstract: Background: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in...
Probing the viability of oxo-coupling pathways in iridium-catalyzed oxygen evolution
Jonathan Graeupner, Ulrich Hintermair, Daria L. Huang, Julianne M. Thomsen, Mike Takase, Jesus Campos, Sara M. Hashmi, Menachem Elimelech, Gary W. Brudvig, Robert H. Crabtree
Oct 14, 2013
A series of Cp*IrIII dimers has been synthesized to elucidate the mechanistic viability of radical oxo-coupling pathways in iridium-catalyzed O2 evolution. The oxidative stability of the precursors towards...
Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon.
Yousuf A Khan, Irwin Jungreis, James C Wright, Jonathan M Mudge, Jyoti S Choudhary, Andrew E Firth, Manolis Kellis
Aug 26, 2020
BACKGROUND: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in mitochondria...
Recommendations for the management of secondary hypogammaglobulinaemia due to B cell targeted therapies in autoimmune rheumatic diseases.
Sonali Wijetilleka, David R Jayne, Chetan Mukhtyar, Aftab Ala, Philip D Bright, Hector Chinoy, Lorraine Harper, Majid A Kazmi, Sorena Kiani-Alikhan, Charles K Li, Siraj A Misbah, Louise Oni, Fiona E Price-Kuehne, Alan D Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Nov 27, 2019
OBJECTIVES: The association of B cell targeted therapies with development of hypogammaglobulinaemia and infection is increasingly recognized. Our aim was to develop consensus recommendations for immunoglobulin replacement...
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research.
Jennifer K Quint, Elisabeth Moore, Adam Lewis, Maimoona Hashmi, Kirin Sultana, Mark Wright, Liam Smeeth, Lia Chatzidiakou, Roderic Jones, Sean Beevers, Sefki Kolozali, Frank Kelly, Benjamin Barratt
Sep 20, 2018
Databases of electronic health records (EHR) are not only a valuable source of data for health research but have also recently been used as a medium through which potential study participants can be screened, located and...
Immunoglobulin replacement for secondary immunodeficiency after B-cell targeted therapies in autoimmune rheumatic disease
Sonali Wijetilleka, Chetan Mukhtyar, David Jayne, Aftab Ala, Philip Bright, Hector Chinoy, Lorraine Harper, Majid Kazmi, Sorena Kiani-Alikhan, Charles Li, Siraj Misbah, Louise Oni, Fiona Price-Kuehne, Alan Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Feb 24, 2020
BACKGROUND: Consensus guidelines are not available for the use of immunoglobulin replacement therapy (IGRT) in patients developing iatrogenic secondary antibody deficiency following B-cell targeted therapy (BCTT) in autoimmune...
Altered Onset Response Dynamics in Somatosensory Processing in Autism Spectrum Disorder.
Sheraz Khan, Javeria A Hashmi, Fahimeh Mamashli, Hari M Bharadwaj, Santosh Ganesan, Konstantinos P Michmizos, Manfred G Kitzbichler, Manuel Zetino, Keri-Lee A Garel, Matti S Hämäläinen, Tal Kenet
Dec 11, 2019
Abnormalities in cortical connectivity and evoked responses have been extensively documented in autism spectrum disorder (ASD). However, specific signatures of these cortical abnormalities remain elusive, with data pointing...
Removing physiological motion from intravital and clinical functional imaging data.
Sean C Warren, Max Nobis, Astrid Magenau, Yousuf H Mohammed, David Herrmann, Imogen Moran, Claire Vennin, James RW Conway, Pauline Mélénec, Thomas R Cox, Yingxiao Wang, Jennifer P Morton, Heidi CE Welch, Douglas Strathdee, Kurt I Anderson, Tri Giang Phan, Michael S Roberts, Paul Timpson
Jun 27, 2019
Intravital microscopy can provide unique insights into the function of biological processes in a native context. However, physiological motion caused by peristalsis, respiration and the heartbeat can present a significant...
FLIM FRET Cell Biology Computational Biology human Intravital Microscopy motion correction MOUSE multiphoton Systems Biology Algorithms Animals Biosensing Techniques Cell Adhesion Computer Simulation Fluorescence Resonance Energy Transfer Guanosine Triphosphate Humans Imaging Three-Dimensional Intestines Intravital Microscopy Mice Microscopy Fluorescence Models Biological Motion Neoplasm Metastasis Neuropeptides Pancreatic Neoplasms Skin Software rac1 GTP-Binding Protein src-Family Kinases
Retained Foreign Body Causing Actinomycosis and Osteomyelitis of Second Metatarsal in Paediatric Foot
Shaik Ajaz, C. Shamsunder, Mohammed Jalal Mohiuddin, Abdul Hameed Parekh, Hashmi Syed Salman Hamid and Varun Vemulapally
Jan 15, 2015
Introduction: Injuries lead to cellulites or abscess formation, if neglected or improperly managed results in osteomyelitis or septic arthritis of foot structures. This is the report of isolated second metatarsal osteomyelitis...
Published by: IJHS Medical Association
Maturation trajectories of cortical resting-state networks depend on the mediating frequency band.
Sheraz Khan, Javeria A Hashmi, Fahimeh Mamashli, Konstantinos Michmizos, Manfred G Kitzbichler, Hari Bharadwaj, Yousra Bekhti, Santosh Ganesan, Keri-Lee A Garel, Susan Whitfield-Gabrieli, Randy L Gollub, Jian Kong, Lucia M Vaina, Kunjan D Rana, Steven M Stufflebeam, Matti S Hämäläinen, Tal Kenet
Jul 24, 2019
The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state...
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