Estrogen fulfills a variety of physiological roles through its nuclear receptors, estrogen receptors (ERs). The action of ERs is modulated and mediated by diverse interacting cofactors. The initial aim of this thesis work was to...
Recurrent gene mutations often cooperate in a predefined stepwise and synergistic manner to alter global transcription, through directly or indirectly remodeling epigenetic landscape on linear and three-dimensional (3D) scales....
Obstructive sleep apnea (OSA) is a global health concern and is typically diagnosed using in-laboratory polysomnography (PSG). However, PSG is highly time-consuming and labor-intensive. We, therefore, developed machine learning...
How neurons are capable of decoding stimulus intensity and translate this information into complex behavioral outputs is poorly defined. Here, we demonstrate that the C. elegans interneuron AIB regulates two types of behaviors...
Purpose The effects of aerobic exercise training on soleus muscle morphology, mitochondria-mediated apoptotic signaling, and atrophy/hypertrophy signaling in ovariectomized rat skeletal muscle were investigated. Methods Female...
Formulate performance optimization problems of big data workflows with various objects; prove complexities of these problems; design and evaluate proposed heuristics using simulations
$\textbf{Background.}$ Increasing human resources in engineering is a key concern for the United States. While some research has considered pathways to doctoral study, there is not yet clear empirical evidence on the role of...
Purpose The effects of aerobic exercise training on soleus muscle morphology, mitochondria-mediated apoptotic signaling, and atrophy/hypertrophy signaling in ovariectomized rat skeletal muscle were investigated. Methods Female...
Inside this issue:
Letter from Jacob Kang '21
Letter from Maureen Cumpstone '79
Letter from Johnny Myers '19
At a Glance
Investment Strategies
Endowment at Work
New at UCIMCO
Women's Fund
Investment Performance
Endowment...
Abstract: A novel transient electronics technology that is capable of completely dissolving or decomposing in certain conditions after a period of operation offers unprecedented opportunities for medical implants, environmental...
Unbalanced phase currents, which flow in transformer windings and distribution wires, cause a significant increase (~33%) of phase energy losses in low voltage (LV, 415 V) networks. However, these additional phase energy losses...
Autism spectrum disorder is an early-onset neurodevelopmental condition. This study aimed to investigate the progressive structural alterations in the autistic brain during early childhood. Structural magnetic resonance imaging...
Phase imbalance widely exists in the UK’s low voltage (415V, LV) distribution networks. The imbalances not only lead to insufficient use of LV network assets but also cause energy losses. They lead to hundreds of millions of...
Formulate bandwidth scheduling problems with various objects; prove complexities of these problems; design and evaluate proposed heuristics using simulations