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Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Secondary Metabolites of Osmanthus fragrans
Chen-Chen Fu, Fa-Ying Xu, Yu-Chen Qian, Hoi-Lun Koo, Yi-Fan Duan, Geng-Min Weng, Tai-Ping Fan, Mo-Xian Chen, Fu-Yuan Zhu
Aug 01, 2022
Osmanthus fragrans (scientific name: Osmanthus fragrans (Thunb.) Lour.) is a species of the Osmanthus genus in the family Oleaceae, and it has a long history of cultivation in China. O. fragrans is edible and is well known for...
CAMKs support development of acute myeloid leukemia.
Xunlei Kang, Changhao Cui, Chen Wang, Guojin Wu, Heyu Chen, Zhigang Lu, Xiaoli Chen, Li Wang, Jie Huang, Huimin Geng, Meng Zhao, Zhengshan Chen, Markus Müschen, Huan-You Wang, Cheng Cheng Zhang
Oct 03, 2018
BACKGROUND: We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also...
acute myeloid leukemia CAMK CREB LILRB2 Leukemic stem cell PirB Animals Calcium-Calmodulin-Dependent Protein Kinases Carcinogenesis Cell Line Tumor Disease Models Animal Disease Progression Humans Leukemia Myeloid Acute Mice Inbred C57BL Neoplastic Stem Cells Receptors Immunologic Signal Transduction
Revealing the Drag Instability in One-fluid Nonideal Magnetohydrodynamic Simulations of a 1D Isothermal C-shock
Abstract
C-type shocks are believed to be ubiquitous in turbulent molecular clouds thanks to ambipolar diffusion. We investigate whether the drag instability in 1D isothermal...
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
Distribution of horseradish peroxidase (HRP)- anti-HRP immune complexes in mouse spleen with special reference to follicular dendritic cells
The distribution of immune complexes has been studied in mouse spleen stimulated to contain many germinal centers (GC?s). Horseradish peroxidase (HRP)-anti-HRP complexes were used as an appropriately precise and sensitive model....
Published by: Rockefeller University
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells.
Baojiang Wu, Yunxia Li, Bojiang Li, Baojing Zhang, Yanqiu Wang, Lin Li, Junpeng Gao, Yuting Fu, Shudong Li, Chen Chen, M Azim Surani, Fuchou Tang, Xihe Li, Siqin Bao
Apr 16, 2021
Naive pluripotency can be maintained in medium with two inhibitors plus leukemia inhibitory factor (2i/LIF) supplementation, which primarily affects canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these...
DNA Methylation DNMTs DIFFERENTIATION Embryonic Stem Cells epigenetic Genomic Imprinting Leukemia Inhibitory Factor MOUSE Pluripotency self-renew Animals Cell Culture Techniques Cell Differentiation Cell Self Renewal Cells Cultured Culture Media DNA (Cytosine-5-)-Methyltransferases DNA Methylation DNA Methyltransferase 3A Gene Expression Regulation Developmental Gene Knockout Techniques Genomic Imprinting Germ Layers Janus Kinases Leukemia Inhibitory Factor Mice Mice Inbred C57BL Mice Transgenic Mouse embryonic stem cells STAT3 Transcription Factor Signal Transduction Transcriptome
Impact of Irradiation on the Pharmacokinetics and Biotransformation of Tamoxifen.
Yung-Yi Cheng, Teresa Zheng, Michael W Chang, Jeffrey W Dalley, Yu-Jen Chen, Tung-Hu Tsai, Chen-Hsi Hsieh
Mar 03, 2022
BACKGROUND: The optimal procedure for combining radiotherapy (RT) with tamoxifen treatment is controversial as RT may alter the pharmacokinetics and biotransformation of tamoxifen. The present study investigated this potential...
Investigation of anterior cingulate cortex gamma-aminobutyric acid and glutamate-glutamine levels in obsessive-compulsive disorder using magnetic resonance spectroscopy.
Yan Li, Chen Cheng Zhang, Kathrin Weidacker, Yingying Zhang, Naying He, Haiyan Jin, Weibo Chen, Valerie Voon, Richard AE Edden, Fuhua Yan
Aug 21, 2019
BACKGROUND: Obsessive-compulsive disorder (OCD) is a relatively common and disabling psychiatric disorder whose pathophysiology is incompletely understood. In this study, we utilized magnetic resonance spectroscopy (MRS) in an...
A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats.
Jane L Tarry-Adkins, Catherine E Aiken, Thomas J Ashmore, Denise S Fernandez-Twinn, Jian-Hua Chen, Susan E Ozanne
Sep 05, 2018
Reduced fetal nutrition and rapid postnatal growth accelerates the aging phenotype in many organ systems; however, effects on the immune system are unclear. We addressed this by studying the thymus from a rat model of...
The Properties of HPMC
Anran Hu, Chen Chen, Michael D Mantle, Bettina Wolf, Lynn F Gladden, Ali Rajabi-Siahboomi, Shahrzad Missaghi, Laura Mason, Colin D Melia
Apr 05, 2019
PURPOSE: Investigate the extended release behaviour of compacts containing mixtures of hydrophilic HPMC and PEO in hydrating media of differing ionic strengths. METHODS: The extended release behaviour of various HPMC:PEO...
Masks for COVID-19.
Wei Deng, Yajun Sun, Xiaoxue Yao, Karpagam Subramanian, Chen Ling, Hongbo Wang, Shauhrat S Chopra, Ben Bin Xu, Jie-Xin Wang, Jian-Feng Chen, Dan Wang, Honeyfer Amancio, Stevin Pramana, Ruquan Ye, Steven Wang
Dec 15, 2021
Sustainable solutions on fabricating and using a face mask to block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread during this coronavirus pandemic of 2019 (COVID-19) are required as society is directed...
Liquid jet leaping from a free surface
We investigate the characteristics of a liquid jet ejected from an inclined tube, which is submerged immediately under a free surface. Jets are classified into three regimes: the curtain regime, transition regime, and column...
Control of Raman Scattering Quantum Interference Pathways in Graphene.
Xue Chen, Sven Reichardt, Miao-Ling Lin, Yu-Chen Leng, Yan Lu, Heng Wu, Rui Mei, Ludger Wirtz, Xin Zhang, Andrea C Ferrari, Ping-Heng Tan
Apr 09, 2023
Quantum Interference Graphite Intercalation Compounds Electron−electron Interaction Electron−phonon Coupling Resonant Raman Scattering
Published by: ACS nano
Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.
Rong-Rong Zhao, Matthew Ackers-Johnson, Justus Stenzig, Chen Chen, Tao Ding, Yue Zhou, Peipei Wang, Shi Ling Ng, Peter Y Li, Gavin Teo, Pauline M Rudd, James W Fawcett, Roger SY Foo
May 10, 2018
BACKGROUND: Heart failure is a leading cause of mortality and morbidity, and the search for novel therapeutic approaches continues. In the monogenic disease mucopolysaccharidosis VI, loss-of-function mutations in arylsulfatase B...
Displacement based multiple wedge slope stability analysis
Paul F McCombie
Jan 01, 2009
A method of slope stability analysis based upon multiple wedges is developed, accounting for kinematics in a similar way to proposals by Srbulov (1997) and Donald and Chen (1999). Instead of relying on almost arbitrary...
Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort.
Kaitlin H Wade, Brian YH Lam, Audrey Melvin, Warren Pan, Laura J Corbin, David A Hughes, Kara Rainbow, Jian-Hua Chen, Katie Duckett, Xiaoming Liu, Jacek Mokrosiński, Alexander Mörseburg, Sam Neaves, Alice Williamson, Chen Zhang, I Sadaf Farooqi, Giles SH Yeo, Nicholas J Timpson, Stephen O'Rahilly
Apr 19, 2021
Mutations in the melanocortin 4 receptor gene (MC4R) are associated with obesity but little is known about the prevalence and impact of such mutations throughout human growth and development. We examined the MC4R coding sequence...
Single Atom Selenium Substitution‐Mediated P‐Type Doping in Polythiophenes toward High‐Performance Organic Electronics and Thermoelectrics
Chen Chen, Ian E Jacobs, Cameron Jellett, Xuechen Jiao, James F Ponder, Boseok Kang, Seon Baek Lee, Yuxuan Huang, Lu Zhang, Martin Statz, Yuanhui Sun, Yue Lin, Keehoon Kang, Xiaojian She, Yuanyuan Hu, Tao ZHANG, Lang Jiang, Christopher R McNeill, Iain McCulloch, Henning Sirringhaus
Jun 11, 2022
RESEARCH ARTICLE RESEARCH ARTICLES chalcogen substitution doping organic electronics polythiophene thermoelectrics
Published by: Advanced Electronic Materials
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
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