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High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
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Properties of cryogenic and low temperature composite materials – A review

This paper reviews the literature published since 1994 related to the behaviour of composite materials at low and cryogenic temperatures. The material properties addressed are: tensile, compressive and shear strength, elastic...

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Properties of cryogenic and low temperature composite materials – A review

This paper reviews the literature published since 1994 related to the behaviour of composite materials at low and cryogenic temperatures. The material properties addressed are: tensile, compressive and shear strength, elastic...

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High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
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Novel filler materials for composite out-of-plane joints
In the manufacture of the out-of-plane joints of composite stiffened panels, such as the connection between skin and T, I, omega shaped stiffeners, a filler material is needed to fill the void between the flanges, web and skin....
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Novel filler materials for composite out-of-plane joints
In the manufacture of the out-of-plane joints of composite stiffened panels, such as the connection between skin and T, I, omega shaped stiffeners, a filler material is needed to fill the void between the flanges, web and skin....
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Stochasticity in protein levels drives colinearity of gene order in metabolic operons of <em>Escherichia coli</em>
In bacterial genomes, gene order is not random. This is most evident when looking at operons, these often encoding enzymes involved in the same metabolic pathway or proteins from the same complex. Is gene order within operons...
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Stochasticity in protein levels drives colinearity of gene order in metabolic operons of <em>Escherichia coli</em>
In bacterial genomes, gene order is not random. This is most evident when looking at operons, these often encoding enzymes involved in the same metabolic pathway or proteins from the same complex. Is gene order within operons...
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Is mere exposure enough? The effects of bilingual environments on infant cognitive development.
Bilinguals purportedly outperform monolinguals in non-verbal tasks of cognitive control (the 'bilingual advantage'). The most common explanation is that managing two languages during language production constantly draws upon...
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Is mere exposure enough? The effects of bilingual environments on infant cognitive development.
Bilinguals purportedly outperform monolinguals in non-verbal tasks of cognitive control (the 'bilingual advantage'). The most common explanation is that managing two languages during language production constantly draws upon...
Is children's weight a public health or a private family issue?

BACKGROUND: The National Child Measurement Programme (NCMP) is a child weight monitoring system in England, taking place in the first and final years of primary school. Many local authorities consider it important to inform...

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Is children's weight a public health or a private family issue?

BACKGROUND: The National Child Measurement Programme (NCMP) is a child weight monitoring system in England, taking place in the first and final years of primary school. Many local authorities consider it important to inform...

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The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication.
The duplication and ninefold symmetry of the Drosophila centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear....
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Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis.
Rcd4 is a poorly characterized Drosophila centriole component whose mammalian counterpart, PPP1R35, is suggested to function in centriole elongation and conversion to centrosomes. Here, we show that rcd4 mutants exhibit fewer...
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High-throughput discovery of novel developmental phenotypes.
Mary E Dickinson, Ann M Flenniken, Xiao Ji, Lydia Teboul, Michael D Wong, Jacqueline K White, Terrence F Meehan, Wolfgang J Weninger, Henrik Westerberg, Hibret Adissu, Candice N Baker, Lynette Bower, James M Brown, L Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J Daly, James M Denegre, Brendan Doe, Mary E Dolan, Sarah M Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R Horner, Chih-Wei Hsu, Sara J Johnson, Sowmya Kalaga, Lance C Keith, Louise Lanoue, Thomas N Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L McElwee, Susan Newbigging, Lauryl MJ Nutter, Kevin A Peterson, Ramiro Ramirez-Solis, Douglas J Rowland, Edward Ryder, Kaitlin E Samocha, John R Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B West, Leeyean Wong, Atsushi Yoshiki, International Mouse Phenotyping Consortium, Jackson Laboratory, Institut Clinique de la Souris (ICS) Infrastructure Nationale PHENOMIN, Charles River Laboratories, MRC Harwell, Toronto Centre for Phenogenomics, Wellcome Trust Sanger Institute, RIKEN BioResource Center, Daniel G MacArthur, Glauco P Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C Skarnes, Monica J Justice, Helen E Parkinson, Mark Moore, Sara Wells, Robert E Braun, Karen L Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R Mark Henkelman, Steve DM Brown, David J Adams, KC Kent Lloyd, Colin McKerlie, Arthur L Beaudet, Maja Bućan, Stephen A Murray
Oct 22, 2020
Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous insight into gene function and congenital disorders. As part of the...
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