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Biochemical and Biological Studies on the Growth of an RNA Containing Bacteriophage

OAI: oai:digitalcommons.rockefeller.edu:student_theses_and_dissertations-1581
Published by: Rockefeller University

Abstract

The growth of the RNA-containing bacteriophage f2 has been studied. DNA synthesis appears normal after phage infection. It is possible to dissociate the synthesis of viral RNA from the synthesis of DNA using thymineless bacteria with fluorinated pyrimidines and Mitomycin C as inhibitors of DNA synthesis. It is concluded that the growth of f2 is independent of DNA synthesis.