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Biochemical and Biological Studies on the Growth of an RNA Containing Bacteriophage

OAI: oai:digitalcommons.rockefeller.edu:student_theses_and_dissertations-1612
Published by: Rockefeller University

Abstract

The growth of the RNA-containing bacteriophage f2 has been studied. DNA synthesis appear normal after phage infection. It is possible to dissociate the synthesis of viral RNA from the synthesis of DNA using thymine-less bacteria with fluorinated pyrimidines and Mitomycin C as inhibitors of DNA synthesis. It is concluded that the growth of f2 is independent of DNA synthesis.