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The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing.
Elsa Boudadi
,
Hannah Stower
,
John A Halsall
,
Charlotte E Rutledge
,
Martin Leeb
,
Anton Wutz
,
Laura P O'Neill
,
Karl P Nightingale
,
Bryan M Turner
OAI: oai:www.repository.cam.ac.uk:1810/244603
Published by:
Abstract
Hoxb genes
Valproic acid
Histone deacetylase
Polycomb repression
Mouse embryonic stem cells
Histone modification
Microarray expression analysis
Retinoic acid
Transcriptional Activation