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Modelling ligand selectivity of serine proteases using integrative proteochemometric approaches improves model performance and allows the multi-target dependent interpretation of features.
Qurrat U Ain
,
Oscar Méndez-Lucio
,
Isidro Cortés Ciriano
,
Thérèse Malliavin
,
Gerard JP van Westen
,
Andreas Bender
OAI: oai:www.repository.cam.ac.uk:1810/246000
Published by:
Abstract
Amino Acid Sequence
Binding Sites
Blood Coagulation Factors
Models
Theoretical
Serine Proteases
Serine Proteinase Inhibitors
Thrombin
Trypsin