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Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death.
Daniela Catanzaro, Edoardo Gaude, Genny Orso, Carla Giordano, Giulia Guzzo, Andrea Rasola, Eugenio Ragazzi, Laura Caparrotta, Christian Frezza, Monica Montopoli
OAI: oai:www.repository.cam.ac.uk:1810/253793
Abstract
PPP cancer metabolism cisplatin Drug Resistance transmitochondrial hybrids Antineoplastic Agents Cell Line Tumor cisplatin DNA Mitochondrial Dose-Response Relationship Drug Drug Resistance Neoplasm Energy Metabolism Enzyme Inhibitors Female Glucose Glucosephosphate Dehydrogenase Glutamine Humans Mitochondria Ovarian Neoplasms Signal Transduction Time Factors