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Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.
Alison Taylor, James A Harker, Kittiphat Chanthong, Philip G Stevenson, Elina I Zuniga, Christopher E Rudd
OAI: oai:www.repository.cam.ac.uk:1810/253803
Abstract
Aminophenols Animals CD8-Positive T-Lymphocytes Cells Cultured Cytotoxicity Immunologic Gene Expression Regulation Glycogen Synthase Kinase 3 Herpesviridae Infections Lymphocytic Choriomeningitis Lymphocytic choriomeningitis virus Maleimides Mice Mice Inbred BALB C Mice Inbred C57BL Programmed Cell Death 1 Receptor RNA Small Interfering Rhadinovirus T-Box Domain Proteins T-Lymphocytes Cytotoxic Viral Load