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Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.

Madeline E Kavanagh, Anthony G Coyne, Kirsty J McLean, Guy G James, Colin W Levy, Leonardo B Marino, Luiz Pedro S de Carvalho, Daniel SH Chan, Sean A Hudson, Sachin Surade, David Leys, Andrew W Munro, Chris Abell

OAI: oai:www.repository.cam.ac.uk:1810/254343

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Abstract

Bacterial Proteins Binding Sites Crystallography X-Ray Cytochrome P-450 Enzyme System Drug Design Enzyme Inhibitors Humans Ligands Mycobacterium tuberculosis Protein Binding Protein Structure Tertiary Tuberculosis