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Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Monica Kasbekar
,
Gerhard Fischer
,
Bryan T Mott
,
Adam Yasgar
,
Marko Hyvönen
,
Helena IM Boshoff
,
Chris Abell
,
Clifton E Barry
,
Craig J Thomas
OAI: oai:www.repository.cam.ac.uk:1810/256537
•
DOI: 10.17863/CAM.484
Published by:
Abstract
Mycobacterium tuberculosis
TCA cycle
Allosteric Regulation
Fumarate Hydratase
selective inhibition
Allosteric Regulation
Crystallography
X-Ray
Fluorescence
Fumarate Hydratase
Mycobacterium tuberculosis