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CCT complex restricts neuropathogenic protein aggregation via autophagy

M Pavel, S Imarisio, FM Menzies, M Jimenez-Sanchez, FH Siddiqi, X Wu, M Renna, CJ O'Kane, DC Crowther, DC Rubinsztein

OAI: oai:www.repository.cam.ac.uk:1810/262038 • DOI: 10.17863/CAM.7278

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Abstract

Animals Ataxin-3 Autophagosomes Autophagy Chaperonin Containing TCP-1 Drosophila Female HeLa Cells Humans Huntingtin Protein Lysosomes Male Mice Transgenic protein aggregation Pathological RNA-Binding Proteins