Demystifying blood stem cell fates

FK Hamey, B Göttgens

OAI: oai:www.repository.cam.ac.uk:1810/264438 • DOI: 10.17863/CAM.9916

Determining the differentiation potential of stem and progenitor cells is essential for understanding their function, yet our ability to do so is limited by the restrictions of experimental assays. Based on single-cell functional and molecular profiling experiments, a new computational approach shows how lineage commitment may occur in human haematopoiesis.

Cell Lineage haematopoietic stem cells stem-cell differentiation