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LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation

M Raab, Y Lu, K Kohler, X Smith, K Strebhardt, CE Rudd

OAI: oai:www.repository.cam.ac.uk:1810/265697 • DOI: 10.17863/CAM.11979

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Abstract

Adaptor Proteins Signal Transducing Cell Cycle Proteins Dendritic Cells Focal Adhesion Kinase 1 Focal Adhesion Kinase 2 GRB2 Adaptor Protein Humans Jurkat Cells Lymphocyte Function-Associated Antigen-1 Membrane Proteins Microtubule-Associated Proteins Phosphoproteins Phosphorylation T-Lymphocytes