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Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway
JR Grainger, KA Smith, JP Hewitson, HJ McSorley, Y Harcus, KJ Filbey, CAM Finney, EJD Greenwood, DP Knox, MS Wilson, Y Belkaid, AY Rudensky, RM Maizels
OAI: oai:www.repository.cam.ac.uk:1810/267316 • DOI: 10.17863/CAM.13314
Abstract
Animals Antigens Helminth Benzamides Cell Proliferation Chronic Disease Dioxoles Forkhead Transcription Factors Gene Expression Regulation host-parasite interactions Mice Mice Inbred BALB C Mice Transgenic Nematospiroides dubius Phosphorylation Protein Serine-Threonine Kinases Receptor Transforming Growth Factor-beta Type II Receptors Transforming Growth Factor beta Signal Transduction Smad2 Protein Smad3 Protein Strongylida Infections T-Lymphocytes Regulatory Th1 Cells Th2 Cells Transforming Growth Factor beta