Abstract
This case report describes an atypical presentation of
cryptococcal infection in a cat initially presented with
multiple persistent pruritic exudative skin lesions, which
did not subside following administration of antibiotics
and corticosteroids. Both fungal culture and feline
immunodeficiency virus (FIV)/feline leukaemia virus
(FeLV) ELISA test yielded negative results. Cytological
examination of the skin scrapings was consistent with
infection by Cryptococcus, which was confirmed by
both postmortem inspection and histopathological
examination of the lesions. The observed multifocal
skin lesions are the result of haematogenous
dissemination of the yeast, which is generally seen in
immunocompromised cats. Clinical signs of systemic
infection by Cryptococcus include apathy and cachexia
and may or may not follow classical nasal disease.
Surprisingly, the cat described in this report was
immunocompetent, presented in good general condition
and with no nasal discharge.