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Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.
Md Saiful Islam
,
Michael A McDonough
,
Rasheduzzaman Chowdhury
,
Joseph Gault
,
Amjad Khan
,
Elisabete Pires
,
Christopher J Schofield
OAI: oai:www.repository.cam.ac.uk:1810/307334
•
DOI: 10.17863/CAM.54424
Published by:
Abstract
2-oxoglutarate and iron dependent dioxygenase
C-5 hydroxylysine
JMJD6
JmjC domain-containing protein 6
RNA Splicing
X-ray crystallography
dioxygenase
enzyme catalysis
enzyme structure
hydroxylase
hydroxylysine (Hyl)
Hypoxia
metalloenzyme
Substrate Specificity
Catalysis
Crystallography
X-Ray
Estrogen Receptor alpha
Humans
Hydroxylation
Jumonji Domain-Containing Histone Demethylases
Kinetics
Lysine
Protein Conformation
Substrate Specificity