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Loss of COX4I1 Leads to Combined Respiratory Chain Deficiency and Impaired Mitochondrial Protein Synthesis.
Kristýna Čunátová, David Pajuelo Reguera, Marek Vrbacký, Erika Fernández-Vizarra, ShuJing Ding, Ian M Fearnley, Massimo Zeviani, Josef Houštěk, Tomáš Mráček, Petr Pecina
OAI: oai:www.repository.cam.ac.uk:1810/317532 • DOI: 10.17863/CAM.64648
Abstract
Cox COX4 OXPHOS biogenesis interdependency CI cIV cIV assembly Complex I complexome profiling knock-out Mitochondria mitochondrial protein synthesis Electron Transport Complex IV Glycolysis HEK293 Cells Humans Mitochondrial Diseases Mitochondrial Proteins Oxidative Phosphorylation Oxygen Consumption Protein Biosynthesis Protein Subunits