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DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing.
Simon R Scutts, Stuart W Ember, Hongwei Ren, Chao Ye, Christopher A Lovejoy, Michela Mazzon, David L Veyer, Rebecca P Sumner, Geoffrey L Smith
OAI: oai:www.repository.cam.ac.uk:1810/286397 • DOI: 10.17863/CAM.33709
Abstract
DNA protein kinase DNA sensing IRF3 signaling Immune Evasion pattern recognition receptor protein C4 vaccinia virus virulence factor Administration Intranasal Animals Cytokines DNA DNA-Activated Protein Kinase Female HEK293 Cells HeLa Cells Humans Immunity Innate Ku Autoantigen Lymphocyte Activation Mice Inbred BALB C Mice Inbred C57BL Mutagenesis Site-Directed Protein Binding Protein Multimerization T-Lymphocytes vaccinia virus Viral Proteins Virulence