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HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites.
Emma L Davies
,
Mahlaqua Noor
,
Eleanor Y Lim
,
Charlotte J Houldcroft
,
Georgina Okecha
,
Claire Atkinson
,
Matthew B Reeves
,
Sarah E Jackson
,
Mark R Wills
OAI: oai:www.repository.cam.ac.uk:1810/346030
•
DOI: 10.17863/CAM.93452
Published by:
Abstract
aging
anti-viral T cells
anti-viral assays
human cytomegalovirus (HCMV)
immune senescence
latent infection
neutralizing antibodies
Aged
Humans
Cytomegalovirus
Antiviral Agents
Leukocytes
Mononuclear
Adaptive Immunity
Virus Replication