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Naturally-occurring serotype 3 Streptococcus pneumoniae strains that lack functional pneumolysin and autolysin have attenuated virulence but induce localized protective immune responses.

Ηαnnah E Wong, Panagiotis Tourlomousis, Gavin K Paterson, Steve Webster, Clare E Bryant

OAI: oai:www.repository.cam.ac.uk:1810/347371 • DOI: 10.17863/CAM.94786

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Abstract

Animals Mice Horses Streptococcus pneumoniae Tumor Necrosis Factor-alpha N-Acetylmuramoyl-L-alanine Amidase Virulence Serogroup Streptolysins Bacterial Proteins Immunity