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Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner.
Cansu Karabiyik
,
Mariella Vicinanza
,
Sung Min Son
,
David C Rubinsztein
OAI: oai:www.repository.cam.ac.uk:1810/323696
•
DOI: 10.17863/CAM.71153
Published by:
Abstract
AMPK
PI(5)P
PIKfyve
ULK1
Autophagy
glucose starvation
mTOR
phagophore
AMP-Activated Protein Kinase Kinases
Autophagosomes
Autophagy
Autophagy-Related Protein-1 Homolog
Cell Line
Gene Expression Regulation
Glucose
Humans
metabolism
Phosphatidylinositol 3-Kinases
Phosphatidylinositol Phosphates
Phospholipids
Protein Kinases
Signal Transduction