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Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
Jonathan Gilley
,
Michael Coleman
,
Oscar Jackson
OAI: oai:www.repository.cam.ac.uk:1810/332540
•
DOI: 10.17863/CAM.79990
Published by:
Abstract
ALS
NADase
SARM1
Genetics
Genomics
human
neuroscience
risk allele
Adult
Aged
Alleles
Amyotrophic Lateral Sclerosis
Animals
Armadillo Domain Proteins
Cytoskeletal Proteins
Female
Humans
Male
Mice
Middle Aged
motor neuron disease
NAD+ Nucleosidase
Nicotinamide Mononucleotide