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DNA-induced spatial entrapment of general transcription machinery can stabilize gene expression in a nondividing cell.

Khayam Javed, Jerome Jullien, Gaurav Agarwal, Nicola Lawrence, Richard Butler, Pantelis Savvas Ioannou, Farhat Nazir, JB Gurdon

OAI: oai:www.repository.cam.ac.uk:1810/334473 • DOI: 10.17863/CAM.81890

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Abstract

Ascl1 Xenopus oocyte liquid–liquid phase separation stable gene expression Transcriptional regulation Animals Cell Differentiation DNA Gene Expression Regulation Humans Oocytes Phosphorylation RNA Polymerase II Templates Genetic Transcription Genetic Xenopus