Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
Anna Vilalta,
Ye Zhou,
Jean Sevalle,
Jennifer K Griffin,
Kanayo Satoh,
David H Allendorf,
Suman De,
Mar Puigdellívol,
Arturas Bruzas,
Miguel A Burguillos,
Roger B Dodd,
Fusheng Chen,
Yalun Zhang,
Patrick Flagmeier,
Lisa-Maria Needham,
Masahiro Enomoto,
Seema Qamar,
James Henderson,
Jochen Walter,
Paul E Fraser,
David Klenerman,
Steven F Lee,
Peter St George-Hyslop,
Guy C Brown
OAI: oai:www.repository.cam.ac.uk:1810/319553 • DOI: 10.17863/CAM.66675