![Cover Image for System.Linq.Enumerable+EnumerablePartition`1[System.Char]](https://coverimages.igi-global.com/images/search-article.png)
Asymmetric synthesis of chiral delta-lactones containing multiple contiguous stereocenters
Jennifer Peed, I P Dominguez, Iwan R Davies, M Cheeseman, James E Taylor, Gabriele Kociok-Kohn, Steven D Bull
OAI: oai:purehost.bath.ac.uk:openaire_cris_publications/6534103f-ebb9-4d8d-a6c4-c5a238cdee62 • DOI: https://doi.org/10.1021/ol2012023
Abstract
A versatile methodology for the asymmetric synthesis of chiral delta-lactones containing multiple contiguous stereocenters has been developed that relies on a series of Evans' aldol, hydroxyl-directed cyclopropanation, methanolysis, and Hg(II) mediated cyclopropane ring-opening reactions for stereocontrol.