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Ratiometric electrochemical detection of alkaline phosphatase

Sean Goggins, Christophe Naz, Barrie J. Marsh, Christopher G. Frost

OAI: oai:purehost.bath.ac.uk:publications/e0d44c75-15a8-46a6-a433-dc40d7b27d16 • DOI: https://doi.org/10.1039/c4cc07693a

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Abstract

A novel ferrocene-derived substrate for the ratiometric electrochemical detection of alkaline phosphatase (ALP) was designed and synthesised. It was demonstrated to be an excellent electrochemical substrate for the ALP-labelled enzyme-linked immunosorbent assay (ELISA).