Hospital based study of clinical and laboratory characteristics of E.coli versus non-E.coli urinary tract infection

1Rakesh Kumar, 1Md. Jamal Uddin, 2Mehre Darakhshan Mehdi, 1Vishal Parmar and 1Pramod Kumar Agrawal

Urinary tract infection (UTI) remains the most common bacterial infection in human population and is one of the most frequently occurring nosocomial infections. This infection represents serious complication in pregnancy, patients with diabetes, polycystic kidney disease, sickle cell anaemia, kidney transplant and in patients with functional or structural anomalies of the urinary tract infections. UTI with serious clinical presentation ( urosepsis, acute pyelonephritis, acute prostatitis, acute exacerbation of chronic pyelonephritis and chronic prostatitis) requires hospitalisation and urgent administration of appropriate empirical antimicrobialtreatment with no time to wait for identification of causative agent by urine culture. We studied 112 UTI patients and divided these patients into two groups : patients with E.coli UTI and patients with non-E.coli UTI. Our study shows certain clinical and laboratory characteristics are indicator of E.coli UTI like fever higher than 38.50C, chills, headache, leucocytosis, cloudiness of urine while fever lower than 38.50C, neutrophilia, and urine specific gravity <1015 are common in non-E.coli UTI (p<0.05). These clinical findings can lead us to early etiological diagnosis of UTI before urine culture detection of causative agents, and to initiate appropriate empirical antibiotic treatment, which can reduce chances of irreversible kidney damage, complications and duration of hospital stay.

E.coli UTI non-E.coli UTI clinical and laboratory characteristics