Maintenance of maternal arterial pressure during spinal anaesthesia in caesarean section

Md. Arshad Imam

A comparative study was performed on 60 patients to observe the effect of intravenous bolus phenylephrine versus mephentermine during hypotension after subarachnoid block (SAB) for maintenance of arterial pressure during spinal anaesthesia in caesarean section. The patients were divided into two groups of 30 each and were randomly allocated to receive an IV bolus of any of the two drugs. Phenylephrine was administered as 500 μg in 1ml bolus IV and Mephentermine was administered as 6mg Inj. Mephentermine Sulphate in 1ml bolus IV. It was observed that systolic arterial pressure was elevated significantly for first six minutes of bolus dose in Phenylephrine group as compared to Mephentermine group.