Assessment of rifampicin resistance in re-treatment cases of pulmonary tuberculosis using gene-xpert

1Muhammad Shoaib Safdar Qureshi, 2Muhammad Rauf ul Hassan and 3Ahtesham Iqbal

Objective: To assess the rifampicin resistance in re-treatment cases of pulmonary tuberculosis using gene-xpert.Material and methods: This cross sectional study was conducted at Department of Pulmonology Bahawal VictoriaHospital, Bahawalpur. Total 145 patients who came for re-treatment of TB either male or female having age 20-60years were selected for this study.Results: Mean age of the patients was 45.79 ± 11.65 years and mean duration of TB was 5.44 ± 2.9 years. Rifampicinresistance was found in 55 (38%) cases by using gene-xpert test. Rifampicin resistance is significantly associated withgender but insignificantly associated with age and duration of TB.Conclusion: In present study very high percentage of rifampicin resistance was found in retreatment cases of TB byusing gen-xpert test. Significant association of gender with rifampicin resistance was noted but insignificantassociation of age and duration of TB with rifampicin resistance was detected.