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Abstract
OBJECTIVE: To differentiate reactive from malignant lymphadenopathy by using color Doppler ultrasonographic findings of intranodal blood vessels and compare ultrasonographic findings with biopsy report.MATERIALS AND METHODS: Color Doppler ultrasonography was performed on 60 consecutive patients of cervical,axillary and inguinal lymphadenopathy by high frequency transducer(7-10 MHz) before performance of surgical biopsy and presence of malignant changes in intranodal angioarchitecture was evaluated in each lymph node and compared with biopsy report. Long axis/Short axis ratio was also evaluated.RESULTS : Blood vessels in benign lymphadenopathy were dilated,whereas the vessels in malignant lymphadenopathy were compressed by tumor cells .The malignant lymphadenopathy showed high resistivity index value whereas the benign lymphadenopathy showed low resistivity index value. Malignant lymphadenopathy showed long axis/short axis ratio less than 2 and benign lymphadenopathy showed long axis/short ratio more than 2.CONCLUSION: Color Doppler spectral waveform analysis allows distinction between lymph nodes affected by benign versus malignant processes. When high resistivity index is identified in affected lymph nodes, it is almost always involved by metastasis.