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Maternal Dexamethasone Treatment Alters Tissue and Circulating Components of the Renin-Angiotensin System in the Pregnant Ewe and Fetus.
Alison J Forhead, Juanita K Jellyman, Miles J De Blasio, Emma Johnson, Dino A Giussani, Fiona Broughton Pipkin, Abigail L Fowden
Jun 18, 2015
Angiotensin II Type 1 Receptor-Dependent GLP-1 and PYY Secretion in Mice and Humans.
Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – identification of selective stimuli for Insulin-like peptide-5 and Glucagonlike peptide-1 co-expressing cells
Frank Reimann, Lawrence Billing, Pierre Larraufie, Jo Lewis, Andrew Leiter, Joyce Li, Brian Lam, Giles Yeo, Deborah Goldspink, Richard Kay, Fiona Gribble
Sep 06, 2019
OBJECTIVE: Enteroendocrine cells (EECs) of the large intestine, found scattered in the epithelial layer, are known to express different hormones, with at least partial co-expression of different hormones in the same cell. Here...
Enteroendocrine Cells Glucagon-like peptide-1 (GLP-1) Insulin-like peptide-5 (INSL5) Serotonin (5-HT) Single cell RNA-sequencing Animals Enteroendocrine Cells Female Glucagon-Like Peptide 1 Insulin Intestine Large Male Mice Mice Inbred C57BL Mice Transgenic Peptide YY Proteins Receptor Angiotensin Type 1 Single-Cell Analysis Transcriptome Tryptophan Hydroxylase
An AGTR1 Variant Worsens Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome
Nonalcoholic fatty liver disease and hypertension are closely related but there has been little genetic evidence to link them. In this issue, Musso et al. provide evidence that a common variant in AGTR1 (A1166C) is associated...
Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult.
Lesia O Kurlak, Hiten D Mistry, Tereza Cindrova-Davies, Graham J Burton, Fiona Broughton Pipkin
Oct 30, 2015
Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells.
Padmapriya Ponnuswamy, Jeremie Joffre, Olivier Herbin, Bruno Esposito, Ludivine Laurans, Christoph J Binder, Thomas F Tedder, Lynda Zeboudj, Xavier Loyer, Andreas Giraud, Yujiao Zhang, Alain Tedgui, Ziad Mallat, Hafid Ait-Oufella
Jun 21, 2018
Angiotensin II (AngII) promotes hypertension, atherogenesis, vascular aneurysm and impairs post-ischemic cardiac remodeling through concerted roles on vascular cells, monocytes and T lymphocytes. However, the role of AngII in B...