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Cover Image for A comparison of the effect of molluscum contagiosum virus MC159 and MC160 proteins on vaccinia virus virulence in intranasal and intradermal infection routes.

A comparison of the effect of molluscum contagiosum virus MC159 and MC160 proteins on vaccinia virus virulence in intranasal and intradermal infection routes.

Sunetra Biswas, Geoffrey L Smith, Edward J Roy, Brian Ward, Joanna L Shisler

Jun 25, 2018

Molluscum contagiosum virus (MCV) causes persistent, benign skin neoplasm in children and adults. MCV is refractive to growth in standard tissue culture and there is no relevant animal model of infection. Here we investigated...

MC159 MC160 intradermal infection molluscum contagiosum virus pathogenesis Poxvirus Administration Intranasal Animals Child Female Humans Injections Intradermal Mice Inbred BALB C Molluscum contagiosum virus NF-kappa B vaccinia virus Viral Proteins Virulence

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An improved technique for the assessment of venom-induced haemorrhage in a murine model.

Timothy P Jenkins, Andrés Sánchez, Álvaro Segura, Mariángela Vargas, María Herrera, Trenton K Stewart, Guillermo León, José María Gutiérrez

May 16, 2018

Haemorrhage is a common clinical manifestation in envenomings caused by bites from snakes of the family Viperidae. Therefore, knowing the haemorrhagic potential of venoms and the capacity of antivenoms to neutralise this effect...

Antivenom Haemorrhage Minimum haemorrhagic dose Neutralisation Snake venom Animals Dose-Response Relationship Drug Hemorrhage Image Processing Computer-Assisted Injections Intradermal Mice Software Viper Venoms

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