Search

Animals Bile Acids and Salts Cell Differentiation Enteroendocrine Cells Female Glucagon-Like Peptide 1 Glucagon-Like Peptide-1 Receptor Humans Jejunum Male Mice Paracrine Communication Receptors G-Protein-Coupled Serotonin Signal Transduction

Our knowledge about the gut microbiota of pigs is still scarce, despite the importance of these animals for biomedical research and agriculture. Here, we present a collection of cultured bacteria from the pig gut, including 110...

Aged 80 and over Animals Bacteria Bile Acids and Salts Biodiversity Clostridium Feces Female Gastrointestinal Microbiome Genes Bacterial Host Specificity Humans Intestines Male Metagenome Multigene Family Phylogeny RNA Ribosomal 16S Swine

OBJECTIVES: The aim of this study was to investigate the electrical properties of ileal Glucagon-like peptide 1 (GLP-1) secreting L-cells using murine organoid cultures and the electrophysiological and intracellular signaling...

Diabetes FFA1 GLP-1 GPBAR1 obesity Organoid Animals Bile Acids and Salts Calcium Cells Cultured Enteroendocrine Cells Fatty Acids Glucagon-Like Peptide 1 Ileum Membrane Potentials Mice Receptors G-Protein-Coupled TRPC Cation Channels

BACKGROUND: The bile acid (BA) pathway plays a role in regulation of food intake and glucose metabolism, based mainly on findings in animal models. Our aim was to determine whether the BA pathway is altered and correctable in...

Administration Oral Bile Acids and Salts Biological Transport Blood Glucose Capsules Cell Line Cholestenones Colon Diabetes mellitus Type 2 Diffusion Chambers Culture Enteroendocrine Cells Fasting Fibroblast Growth Factors Fructosamine Gene Expression Glucagon-Like Peptide 1 Homeostasis Humans Ileum Insulin obesity Postprandial Period Primary Cell Culture Receptors G-Protein-Coupled

Adolescent Adult Alleles Amino Acid Substitution Bile Acids and Salts Bone Density Child Female Follow-Up Studies Homozygote Humans Hypercholesterolemia Lipid Metabolism Male Middle Aged Organic Anion Transporters Sodium-Dependent Precision Medicine Symporters Exome Sequencing Young Adult

Bile Acids and Salts Child Clostridiales Critical Illness Feces Gastrointestinal Microbiome Humans RNA Ribosomal 16S

Bile acids are signalling molecules, which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex bile acids in the intestinal lumen and decrease intestinal FXR activity. The BAS-BA...

Animals Anticholesteremic Agents Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Bile Acids and Salts Blood Glucose Colesevelam Hydrochloride Colon Diet High-Fat Enteroendocrine Cells Glucagon-Like Peptide 1 Glycolysis Humans Ileum Insulin Insulin Secretion Insulin-Secreting Cells Intestinal Mucosa Intestines Jejunum Mice Mice Knockout Mice Obese Nuclear Proteins obesity Proglucagon RNA Messenger Receptors Cytoplasmic and Nuclear Receptors G-Protein-Coupled Sequestering Agents Signal Transduction Transcription Factors

OBJECTIVE: Bile acids (BAs) facilitate fat absorption and may play a role in glucose and metabolism regulation, stimulating the secretion of gut hormones. The relative importance and mechanisms involved in BA-stimulated...

Bile-acids GLP-1 Insulin Neurotensin PYY TGR5 Animals Bile Acids and Salts COS Cells Cells Cultured Chlorocebus aethiops Gastric Inhibitory Polypeptide Glucagon-Like Peptide 1 Intestinal Mucosa Male Mice Mice Inbred C57BL Pancreas Peptide YY Rats Rats Wistar Receptors G-Protein-Coupled

Animals Bile Acids and Salts Calcium Cells Cultured Cyclic AMP Enteroendocrine Cells Glucagon-Like Peptide 1 Intestine Small Intracellular Space Male Mice Knockout Mice Transgenic Microscopy Fluorescence Rats Wistar Receptors G-Protein-Coupled Taurodeoxycholic Acid Taurolithocholic Acid Tissue Culture Techniques

Caliciviruses cyclooxygenases Nitric oxide prostaglandin E2 Sapovirus Animals Bile Acids and Salts Caliciviridae Infections Cell Line Cells Cultured Cyclooxygenase 1 Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Dinoprostone Gene Expression Nitric oxide RNA Interference RNA Small Interfering Sapovirus Signal Transduction Swine Virus Replication

Bile Acids and Salts Cholestasis Consanguinity DNA Helicases Exome Female Frameshift Mutation Humans Infant Liver Diseases Male Oxidoreductases Phenotype Sequence Analysis DNA Severity of Illness Index

BACKGROUND: Serum bile acids (SBAs) are frequently measured in dogs. However, there is limited data comparing SBAs in different liver diseases diagnosed according to standardized histological criteria. OBJECTIVES: To compare...

WSAVA canine liver disease Cholestasis hepatobiliary Animals Bile Acids and Salts Dog Diseases Dogs Liver Cirrhosis Liver Diseases Retrospective Studies