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Long QT Syndrome 3 (LQTS3) arises from gain-of-function Nav1.5 mutations, prolonging action potential repolarisation and electrocardiographic (ECG) QT interval, associated with increased age-dependent risk for major arrhythmic...

Adrenergic Agents aging Animals Cardiac Conduction System Disease Disease Models Animal Electrocardiography Fibrosis Heart Function Tests Humans Long QT Syndrome Mice Phenotype

ECG QT interval action-potential duration mouse heart Action Potentials Animals Arrhythmias Cardiac Brugada Syndrome Cardiac Conduction System Disease Electrocardiography Heart Heart Conduction System Long QT Syndrome Male Mice