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Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Alessandra Stangherlin, Joseph L Watson, David CS Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D Beale, Edward A Hayter, Alina Guna, Alison J Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M Voorhees, David A Bechtold, Emmanuel Derivery, Rachel S Edgar, Peter Newham, John S O'Neill
Dec 15, 2021
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic...
Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations.
Hanne Hoitzing, Payam A Gammage, Lindsey Van Haute, Michal Minczuk, Iain G Johnston, Nick S Jones
Sep 11, 2019
The dynamics of the cellular proportion of mutant mtDNA molecules is crucial for mitochondrial diseases. Cellular populations of mitochondria are under homeostatic control, but the details of the control mechanisms involved...
The cytotoxic effect of TiF4 and NaF on fibroblasts is influenced by the experimental model, fluoride concentration and exposure time.
Priscila Maria Aranda Salomão, Flávia Amadeu de Oliveira, Paula Danielle Rodrigues, Luana Polioni Al-Ahj, Kellen Cristina da Silva Gasque, Pia Jeggle, Marilia Afonso Rabelo Buzalaf, Rodrigo Cardoso de Oliveira, John Michael Edwardson, Ana Carolina Magalhães
Oct 22, 2018
OBJECTIVE: Titanium tetrafluoride (TiF4) has shown promising effect in preventing tooth lesions. Therefore, we compared the cytotoxicity of TiF4 with sodium fluoride (NaF) (already applied in Dentistry) considering different...
Cooperative contractility
William Ronan, Robert M McMeeking, Christopher S Chen, J Patrick McGarry, Vikram S Deshpande
Jan 30, 2015
F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis.
Murielle P Serres, Matthias Samwer, Binh An Truong Quang, Geneviève Lavoie, Upamali Perera, Dirk Görlich, Guillaume Charras, Mark Petronczki, Philippe P Roux, Ewa K Paluch
Jul 02, 2020
Most metazoan cells entering mitosis undergo characteristic rounding, which is important for accurate spindle positioning and chromosome separation. Rounding is driven by contractile tension generated by myosin motors in the...