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In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
Cell origin and culture history determine successful integration of neural precursor transplants into the dentate gyrus of the adult rat.
In-vitro Optimization of Nanoparticle-Cell Labeling Protocols for In-vivo Cell Tracking Applications.
O Betzer, R Meir, T Dreifuss, K Shamalov, M Motiei, A Shwartz, K Baranes, CJ Cohen, N Shraga-Heled, R Ofir, G Yadid, R Popovtzer
Aug 08, 2017
Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism.
Animals Apoptosis Axonal Transport Cell Tracking Cholera Toxin Choroidal Neovascularization Diabetes mellitus Experimental Disease Models Animal Gene Expression Regulation HSP27 Heat-Shock Proteins Intravitreal Injections Male Mice Mice Transgenic Phosphorylation Retinal Ganglion Cells Signal Transduction Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-2 p38 Mitogen-Activated Protein Kinases
A track of the clones
Anne-Marie Lyne, David G Kent, Elisa Laurenti, Kerstin Cornils, Ingmar Glauche, Leïla Perié
Dec 17, 2018
Cell Lineage Cell Separation Cell Tracking Clinical Trials as Topic Clone Cells DNA barcoding Taxonomic DNA Transposable Elements Data Display Forecasting Genetic Markers Genetic Therapy Guidelines as Topic Hematopoiesis Models Biological Mosaicism Reproducibility of Results Research Design Stem Cells Virus Integration
Mechanical Coupling Coordinates the Co-elongation of Axial and Paraxial Tissues in Avian Embryos.
Tissues undergoing morphogenesis impose mechanical effects on one another. How developmental programs adapt to or take advantage of these effects remains poorly explored. Here, using a combination of live imaging, modeling, and...
cell motility Cell Polarity Convergence Coupling elongation Feedback Mechanical forces neural tube (NT) notochord (NC) presomitic mesoderm (PSM) Animals Biomechanical Phenomena Body Patterning Cell Movement Cell Polarity Cell Tracking Chick Embryo Computer Simulation Embryo Nonmammalian Mesoderm Organogenesis Quail
Haematopoietic stem cells in perisinusoidal niches are protected from ageing.
Mehmet Saçma, Johannes Pospiech, Ruzhica Bogeska, Walter de Back, Jan-Philipp Mallm, Vadim Sakk, Karin Soller, Gina Marka, Angelika Vollmer, Rebekah Karns, Nina Cabezas-Wallscheid, Andreas Trumpp, Simón Méndez-Ferrer, Michael D Milsom, Medhanie A Mulaw, Hartmut Geiger, Maria Carolina Florian
Nov 15, 2019
With ageing, intrinsic haematopoietic stem cell (HSC) activity decreases, resulting in impaired tissue homeostasis, reduced engraftment following transplantation and increased susceptibility to diseases. However, whether ageing...
aging Animals Bone Marrow Capillaries Cell Differentiation Cell Division Cell Polarity Cell Tracking Doxycycline Fluorouracil Gene Expression Regulation Genes Reporter Green Fluorescent Proteins Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells Histones Homeostasis Jagged-2 Protein Mice Mice Inbred C57BL Mice Transgenic Myeloablative Agonists Stem Cell Niche
Extracting fluorescent reporter time courses of cell lineages from high-throughput microscopy at low temporal resolution
Mike J Downey, Danuta M Jeziorska, Sascha Ott, T Katherine Tamai, Georgy Koentges, Keith W Vance, Till Bretschneider
Jan 01, 0001
The extraction of fluorescence time course data is a major bottleneck in high-throughput live-cell microscopy. Here we present an extendible framework based on the open-source image analysis software ImageJ, which aims in...
Extracting fluorescent reporter time courses of cell lineages from high-throughput microscopy at low temporal resolution
Mike J Downey, Danuta M Jeziorska, Sascha Ott, T Katherine Tamai, Georgy Koentges, Keith W Vance, Till Bretschneider
Jan 01, 0001
The extraction of fluorescence time course data is a major bottleneck in high-throughput live-cell microscopy. Here we present an extendible framework based on the open-source image analysis software ImageJ, which aims in...
Nanoparticle vesicle encoding for imaging and tracking cell populations.
Paul Rees, John W Wills, M Rowan Brown, James Tonkin, Mark D Holton, Nicole Hondow, Andrew P Brown, Rik Brydson, Val Millar, Anne E Carpenter, Huw D Summers
Aug 13, 2019
For phenotypic behavior to be understood in the context of cell lineage and local environment, properties of individual cells must be measured relative to population-wide traits. However, the inability to accurately identify...
NucliTrack
Summary: Live imaging studies give unparalleled insight into dynamic single cell behaviours and fate decisions. However, the challenge of reliably tracking single cells over long periods of time limits both the throughput and...
In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
Immunotherapy Cell therapy PET/CT reporter genes Cell Tracking Pet/mri Immuno-PET direct cell labelling
Published by: Cancers
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, R Salari, J Le Quesne, DA Moore, S Veeriah, R Rosenthal, T Marafioti, E Kirkizlar, TBK Watkins, N McGranahan, S Ward, L Martinson, J Riley, F Fraioli, M Al Bakir, E Grönroos, F Zambrana, R Endozo, WL Bi, FM Fennessy, N Sponer, D Johnson, J Laycock, S Shafi, J Czyzewska-Khan, A Rowan, T Chambers, N Matthews, S Turajlic, C Hiley, SM Lee, MD Forster, T Ahmad, M Falzon, E Borg, D Lawrence, M Hayward, S Kolvekar, N Panagiotopoulos, SM Janes, R Thakrar, A Ahmed, F Blackhall, Y Summers, D Hafez, A Naik, A Ganguly, S Kareht, R Shah, L Joseph, A Marie Quinn, PA Crosbie, B Naidu, G Middleton, G Langman, S Trotter, M Nicolson, H Remmen, K Kerr, M Chetty, L Gomersall, DA Fennell, A Nakas, S Rathinam, G Anand, S Khan, P Russell, V Ezhil, B Ismail, M Irvin-Sellers, V Prakash, JF Lester, M Kornaszewska, R Attanoos, H Adams, H Davies, D Oukrif, AU Akarca, JA Hartley, HL Lowe, S Lock, N Iles, H Bell, Y Ngai, G Elgar, Z Szallasi, RF Schwarz, J Herrero, A Stewart, SA Quezada, KS Peggs, P Van Loo, C Dive, CJ Lin, M Rabinowitz, HJWL Aerts, A Hackshaw, JA Shaw, BG Zimmermann, TRACERx consortium, PEACE consortium, C Swanton
Mar 19, 2019
The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour...
Biopsy Carcinoma Non-Small-Cell Lung Cell Lineage Cell Tracking Clone Cells DNA Mutational Analysis DNA Neoplasm Disease Progression Drug Resistance Neoplasm Early Detection of Cancer evolution Molecular Humans Limit of Detection Lung Neoplasms Multiplex Polymerase Chain Reaction Neoplasm Metastasis Neoplasm Recurrence Local Postoperative care Reproducibility of Results Tumor Burden
In Vivo Cell Tracking Using PET
Cell therapy is a rapidly evolving field involving a wide spectrum of therapeutic cells for personalised medicine in cancer. In vivo imaging and tracking of cells can provide useful information for improving the accuracy...
Different temporal requirements for tartan and wingless in the formation of contractile interfaces at compartmental boundaries.
Poisson-event-based analysis of cell proliferation.
A protocol for the assessment of cell proliferation dynamics is presented. This is based on the measurement of cell division events and their subsequent analysis using Poisson probability statistics. Detailed analysis of...
Ex vivo MRI cell tracking of autologous mesenchymal stromal cells in an ovine osteochondral defect model.
Hareklea Markides, Karin J Newell, Heike Rudorf, Lia Blokpoel Ferreras, James E Dixon, Robert H Morris, Martin Graves, Joshua Kaggie, Frances Henson, Alicia J El Haj
Feb 07, 2019
BACKGROUND: Osteochondral injuries represent a significant clinical problem requiring novel cell-based therapies to restore function of the damaged joint with the use of mesenchymal stromal cells (MSCs) leading research efforts....
MRI mesenchymal stromal cells osteochondral Pre-clinical. Translational SPIONs tracking Animals Bone Marrow Cells Cell Differentiation Cell Survival Cell Tracking Ferric Compounds Knee Joint Magnetic Resonance Imaging Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells Sheep Synovial Membrane
Mathematical imaging methods for mitosis analysis in live-cell phase contrast microscopy
JS Grah, JA Harrington, SB Koh, JA Pike, A Schreiner, M Burger, C-B Schönlieb, S Reichelt
May 02, 2017
Metastatic-niche labelling reveals parenchymal cells with stem features.
Luigi Ombrato, Emma Nolan, Ivana Kurelac, Antranik Mavousian, Victoria Louise Bridgeman, Ivonne Heinze, Probir Chakravarty, Stuart Horswell, Estela Gonzalez-Gualda, Giulia Matacchione, Anne Weston, Joanna Kirkpatrick, Ehab Husain, Valerie Speirs, Lucy Collinson, Alessandro Ori, Joo-Hyeon Lee, Ilaria Malanchi
Aug 29, 2019
Animals Breast Neoplasms Cell Differentiation Cell Lineage Cell Tracking Coculture Techniques Epithelial Cells Female Humans Luminescent Proteins Lung Neoplasms Male Mice Neoplasm Metastasis Neoplastic Stem Cells Neutrophils Organoids Parenchymal Tissue Staining and Labeling Stem Cell Niche Tumor Microenvironment