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Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murine RyR2-P2328S hearts.
SC Salvage, JH King, KH Chandrasekharan, DIG Jafferji, L Guzadhur, HR Matthews, CL-H Huang, JA Fraser
May 29, 2015
CPVT Na+ currents atrial arrhythmia conduction velocity flecainide ryanodine receptor Animals Anti-Arrhythmia Agents Atrial fibrillation Flecainide Ion Channel Gating Membrane Potentials Mice Mutation NAV1.5 Voltage-Gated Sodium Channel Ryanodine Receptor Calcium Release Channel sodium Treatment Outcome Voltage-Gated Sodium Channel Blockers